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US9969749, Example 3-1 PubChem CID 121265966
CN(C)C1CCC(Nc2ncnc3ccc(-c4cncc(O)c4)cc23)CC1 -
cis or trans-N,N- dimethyl-N''''-[6-(pyridin- 3-yl)quinazolin-4- yl]cyclohexane-1,4- diamine PubChem CID 121266042
CN(C)C1CCC(Nc2ncnc3ccc(-c4cccnc4)cc23)CC1 -
cis or trans-N,N- dimethyl-N''''-[6-(pyridin- 4-yl)quinazolin-4- yl]cyclohexane-1,4- diamine PubChem CID 121266059
CN(C)C1CCC(Nc2ncnc3ccc(-c4ccncc4)cc23)CC1 -
2-chloro-5-{4-[(trans-4- morpholin-4- ylcyclohexyl)amino] quinazolin-6-yl}pyridin- 3-ol PubChem CID 130446823
Oc1cc(-c2ccc3ncnc(NC4CCC(N5CCOCC5)CC4)c3c2)cnc1Cl -
5-[4-[[trans-4-(4,4-Difluoro-1-piperidinyl)cyclohexyl]amino]-6-quinazolinyl]-2-fluoro-3-pyridinol CAS 1899036-21-5 PubChem CID 121266043
Oc1cc(-c2ccc3ncnc(NC4CCC(N5CCC(F)(F)CC5)CC4)c3c2)cnc1F -
5-(4-{[trans-4-(3- methoxyazetidin-1- yl)cyclohexyl]amino} quinazolin-6-yl)pyridin-3-ol PubChem CID 121254786
COC1CN(C2CCC(Nc3ncnc4ccc(-c5cncc(O)c5)cc34)CC2)C1 -
6-(5-amino-6- fluoropyridin-3-yl)-N- {trans-4-[3-(morpholin- 4-ylmethyl)piperidin-1- yl]cyclohexyl}quinazolin- 4-amine PubChem CID 130446821
Nc1cc(-c2ccc3ncnc(NC4CCC(N5CCCC(CN6CCOCC6)C5)CC4)c3c2)cnc1F -
6-[5- (methylamino)pyridin-3- yl]-N-{trans-4-[(3S)-3- (morpholin-4- ylmethyl)piperidin-1- yl]cyclohcxyl}quinazolin- 4-amine PubChem CID 130446856
CNc1cncc(-c2ccc3ncnc(NC4CCC(N5CCC[C@@H](CN6CCOCC6)C5)CC4)c3c2)c1 -
6-[5- (methylamino)pyridin-3- yl]-N-{trans-4-[(3R)-3- (morpholin-4- ylmethyl)piperidin-1- yl]cyclohexyl}quinazolin- 4-amine PubChem CID 130446908
CNc1cncc(-c2ccc3ncnc(NC4CCC(N5CCC[C@H](CN6CCOCC6)C5)CC4)c3c2)c1 -
trans-N''-[6-(5-fluoro-6- methoxypyridin-3- yl)quinazolin-4-yl]-N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254768
COc1ncc(-c2ccc3ncnc(NC4CCC(N(C)C)CC4)c3c2)cc1F -
trans-N''-{6-[5-(2- methoxyethoxy)pyridin- 3-yl]quinazolin-4-yl}- N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254771
COCCOc1cncc(-c2ccc3ncnc(NC4CCC(N(C)C)CC4)c3c2)c1 -
cis or trans-N''-[6-(6- aminopyridin-3- yl)quinazolin-4-yl]-N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254779
CN(C)C1CCC(Nc2ncnc3ccc(-c4ccc(N)nc4)cc23)CC1 -
trans-N''-[6-(5- methoxypyridin-3- yl)quinazolin-4-yl]-N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254785
COc1cncc(-c2ccc3ncnc(NC4CCC(N(C)C)CC4)c3c2)c1 -
trans-N''-[6-(3- methoxypyridin-4- yl)quinazolin-4-yl]-N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254791
COc1cnccc1-c1ccc2ncnc(NC3CCC(N(C)C)CC3)c2c1 -
trans-N''-[6-(5- fluoropyridin-3- yl)quinazolin-4-yl]-N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254800
CN(C)C1CCC(Nc2ncnc3ccc(-c4cncc(F)c4)cc23)CC1 -
trans-N''-[6-(4- methoxypyridin-3- yl)quinazolin-4-yl]-N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254813
COc1ccncc1-c1ccc2ncnc(NC3CCC(N(C)C)CC3)c2c1 -
trans-N''-[6-(3- fluoropyridin-4- yl)quinazolin-4-yl]-N,N- dimethylcyclohexane- 1,4-diamine PubChem CID 121254816
CN(C)C1CCC(Nc2ncnc3ccc(-c4ccncc4F)cc23)CC1 -
6-(5-aminopyridin-3- yl)-N-(trans-4- morpholin-4- ylcyclohexyl)quinazolin- 4-amine PubChem CID 121265982
Nc1cncc(-c2ccc3ncnc(NC4CCC(N5CCOCC5)CC4)c3c2)c1 -
2-[5-(4-{[trans-4- (morpholin-4- yl)cyclohexyl]amino} quinazolin-6-yl)pyridin-3- yl]propan-2-ol PubChem CID 121266104
CC(C)(O)c1cncc(-c2ccc3ncnc(NC4CCC(N5CCOCC5)CC4)c3c2)c1 -
N-[trans-4-(4,4- difluoropiperidin-1- yl)cyclohexyl]-6-[6- fluoro-5- (methylamino)pyridin-3- yl]quinazolin-4-amine PubChem CID 121266112
CNc1cc(-c2ccc3ncnc(NC4CCC(N5CCC(F)(F)CC5)CC4)c3c2)cnc1F