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US11702418, Example 3-5 PubChem CID 156526868
CNCc1ccccc1-c1csc([C@@H](C)Nc2nncc3cnc(N4CCNC(=O)C4)cc23)c1 -
US11702418, Example 5-3 PubChem CID 156527263
CNCc1cccc([C@@H](C)Nc2nnc(C)c3cc(OC)c(OC)cc23)c1C -
3-((R)-1-((7-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-4-((methylamino)methyl)pyrido[3,4-d]pyridazin-1-yl)amino)ethyl)-2-methylbenzonitrile PubChem CID 158547709
Cc1c(C#N)cccc1[C@@H](C)Nc1nnc(CN(C)C(=O)OC(C)(C)C)c2cnc(N3C[C@H]4C[C@@H]3CO4)cc12 -
(R)-3-(1-((5-fluoro-7-(3-hydroxy-3-methylazetidin-1-yl)-4-methylphthalazin-1-yl)amino)ethyl)-2-methylbenzonitrile PubChem CID 156495905
Cc1c(C#N)cccc1[C@@H](C)Nc1nnc(C)c2c(F)cc(N3CC(C)(O)C3)cc12 -
1-(3-((R)-1-((7-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-4-methylpyrido[3,4-<7]pyridazin-1-yl)amino)ethyl)-2-fluorophenyl)-1,1-difluoro-2-methylpropan-2-ol PubChem CID 156495566
Cc1nnc(NC(C)c2cccc(C(F)(F)C(C)(C)O)c2F)c2cc(Cl)ncc12 -
3-((R)-1-((7-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-4-((di methyl amino)methyl)pyrido[3,4-b]pyridazin-1-yl)amino)ethyl)-2-methylbenzonitrile PubChem CID 156496007
Cc1c(C#N)cccc1[C@@H](C)Nc1nnc(CN(C)C)c2cnc(N3C[C@H]4C[C@@H]3CO4)cc12 -
(R)-3-methyl-5-(1-((4-methyl-7-morpholinopyrido[3,4-b]pyridazin-1-yl)amino)ethyl)benzonitrile PubChem CID 156495734
Cc1cc(C#N)cc([C@@H](C)Nc2nnc(C)c3cnc(N4CCOCC4)cc23)c1 -
N—((R)-1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)-4-methyl-7-(((S)-tetrahydrofuran-3-yl)oxy)phthalazin-1-amine PubChem CID 165390565
Cc1nnc(N[C@H](C)c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)c2cc(O[C@H]3CCOC3)ccc12 -
4-methyl-N—((R)-1-(5-(2-((methylamino)methyl(phenyl)thiophen-2-yl)ethyl)-7-(((S)-tetrahydrofuran-3-yl)oxy)phthalazin-1-amine PubChem CID 156495709
CNCc1ccccc1-c1ccc([C@@H](C)Nc2nnc(C)c3ccc(O[C@H]4CCOC4)cc23)s1 -
(R)-3-methyl-5-(1-((4-methyl-7-morpholinophthalazin-1-yl)amino)ethyl)benzonitrile PubChem CID 156495788
Cc1cc(C#N)cc([C@@H](C)Nc2nnc(C)c3ccc(N4CCOCC4)cc23)c1 -
(R)-3-(1-((4-methyl-7-morpholinopyrido[3,4-d]pyridazin-1-yl)amino)ethyl)-5-(trifluoromethyl)phenol PubChem CID 156495983
Cc1nnc(N[C@H](C)c2cc(OCc3ccccc3)cc(C(F)(F)F)c2)c2cc(N3CCOCC3)ncc12 -
3-((R)-1-((5-fluoro-7-((R)-hexahydro-2H,6H-pyrasine[1,2-c][1,3]oxazin-2-yl)-4-methylphthalazin-1-yl)amino)ethyl)-2-methylbenzonitrile PubChem CID 168474921
COC(=O)c1cc(Br)c(C(F)(F)F)c(F)c1I