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US11572374, Example 12-2-3 PubChem CID 150141350
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)[C@@H]1CC[C@H](c3cc(Cl)ccc3Cl)C1)C2 -
N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-3-(2,5- dichlorophenyl)cyclopentanecarboxamide PubChem CID 166027538
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)C1CCC(c3cc(Cl)ccc3Cl)C1)C2 -
N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-3-(4- fluorobenzyl)benzamide PubChem CID 167339607
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)c1cccc(Cc3ccc(Cl)cc3)c1)C2 -
(2E)-3-(5-chloro-1H-indazol-3-yl)-N- ((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-methyl-2- propenamide PubChem CID 151625965
C/C(=C\c1[nH]nc2ccc(Cl)cc12)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N -
(2E)-3-(5-chloro-1-benzothiophen-3-yl)-N- ((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-methyl-2- propenamide PubChem CID 162690873
C/C(=C\c1csc2ccc(Cl)cc12)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N -
(2E)-3-(5-chloro-1-ethyl-1H-indol-3-yl)-N- ((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-methyl-2- propenamide PubChem CID 162690907
CCn1cc(/C=C(\C)C(=O)N[C@@H]2C[C@@H]3CC[C@H]2N3C#N)c2cc(Cl)ccc21 -
(3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-1-(3-cyano-6- (trifluoromethyl)-2-pyridinyl)-N-methyl-3- pyrrolidinecarboxamide PubChem CID 162690615
CN(C(=O)[C@H]1CCN(c2nc(C(F)(F)F)ccc2C#N)C1)[C@@H]1C[C@@H]2CC[C@H]1N2C#N -
(2E)-3-(5-chloro-1-ethyl-1H-pyrrolo[2,3- b]pyridin-3-yl)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-propenamide PubChem CID 162690650
CCn1cc(/C=C/C(=O)N[C@@H]2C[C@@H]3CC[C@H]2N3C#N)c2cc(Cl)cnc21 -
2-(3-bromo-2-cyanophenoxy)-N- ((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)acetamide PubChem CID 162690730
N#Cc1c(Br)cccc1OCC(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N -
2-(3-chlorophenyl)-N-((1R,2R,4S)-7-cyano- 7-azabicyclo[2.2.1]heptan-2-yl)-1,3-oxazole- 5-carboxamide PubChem CID 162690953
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)c1cnc(-c3cccc(Cl)c3)o1)C2 -
N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-6-(2-methyl-2- phenyl-4-morpholinyl)-4- pyrimidinecarboxamide PubChem CID 166027578
CC1(c2ccccc2)CN(c2cc(C(=O)N[C@@H]3C[C@@H]4CC[C@H]3N4C#N)ncn2)CCO1 -
(3E)-4-(3-chlorophenyl)-N-((1R,2R,4S)-7- cyano-7-azabicyclo[2.2.1]heptan-2-yl)-3- butenamide PubChem CID 151035372
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)C/C=C/c1cccc(Cl)c1)C2 -
3'-bromo-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)[biphenyl]-3- carboxamide PubChem CID 162690833
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)c1cccc(-c3cccc(Br)c3)c1)C2 -
(1S,3S)-N-((1R,2R,4S)-7-cyano-7-azabicyclo[2.2.1]heptan-2-yl)-3-(2,5-dichlorophenyl)cyclopentanecarboxamide PubChem CID 162690829
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)[C@H]1CC[C@@H](c3cc(Cl)ccc3Cl)C1)C2 -
4-(3-chlorophenyl)-N-((1R,2R,4S)-7-cyano- 7-azabicyclo[2.2.1]heptan-2-yl)-2- pyridinecarboxamide PubChem CID 162690928
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)c1cc(-c3cccc(Cl)c3)ccn1)C2 -
(3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-4-(2,5- dichlorophenyl)-2-methoxy-3-butenamide PubChem CID 166027451
COC(/C=C/c1cc(Cl)ccc1Cl)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N -
2',5'-dichloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)[biphenyl]-3- carboxamide PubChem CID 166027536
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)c1cccc(-c3cc(Cl)ccc3Cl)c1)C2 -
N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-3-(4- cyanophenoxy)benzamide PubChem CID 151888364
N#Cc1ccc(Oc2cccc(C(=O)N[C@@H]3C[C@@H]4CC[C@H]3N4C#N)c2)cc1 -
(3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-4-(2,5- dichlorophenyl)-N-methyl-3-butenamide PubChem CID 162690646
CN(C(=O)C/C=C/c1cc(Cl)ccc1Cl)[C@@H]1C[C@@H]2CC[C@H]1N2C#N -
(3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-4-(2,5- dichlorophenyl)-3-butenamide PubChem CID 162690751
N#CN1[C@H]2CC[C@@H]1[C@H](NC(=O)C/C=C/c1cc(Cl)ccc1Cl)C2