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US10189841, Compound I-1 PubChem CID 129139561
Cc1cc(C)n(-c2ccc(Cn3c(=O)[nH]c4cnc(-c5ccccc5C(C)C)nc43)cc2)n1 -
7-Methyl-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-(2-propan-2-ylpyridin-3-yl)purin-8-one PubChem CID 129139472
CC(C)c1ncccc1-c1ncc2c(n1)n(Cc1ccc(-c3nc(C(F)(F)F)cn3C)cc1)c(=O)n2C -
9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-(2-propan-2-ylpyridin-3-yl)-7H-purin-8-one PubChem CID 129139748
CC(C)c1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C)cc3)c2n1 -
2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- PubChem CID 129139863
CC(C)c1ccccc1-c1ncc2c(n1)n(Cc1ccc(-c3cnnn3C)cc1)c(=O)n2C -
US10189841, Compound I-12 PubChem CID 129139982
CC(C)c1ncccc1-c1ncc2c(n1)n(Cc1ccc(-n3cccn3)cc1)c(=O)n2C -
7,9-Dihydro-2-[2-(1-methylethyl)phenyl]-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]-8H-purin-8-one CAS 2098211-50-6 PubChem CID 129139687
CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C)cc3)c2n1 -
2-[3-Fluoro-2-(1-methylethyl)phenyl]-7,9-dihydro-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]-8H-purin-8-one CAS 2098212-05-4 PubChem CID 129140207
CC(C)c1c(F)cccc1-c1ncc2[nH]c(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C)cc3)c2n1 -
9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-[2-[3-(trifluoromethyl)azetidin-1-yl]pyridin-3-yl]-7H-purin-8-one PubChem CID 129139805
Cn1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)[nH]c3cnc(-c4cccnc4N4CC(C(F)(F)F)C4)nc32)cc1 -
9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-(2-piperidin-1-ylpyridin-3-yl)-7H-purin-8-one PubChem CID 129139875
Cn1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)[nH]c3cnc(-c4cccnc4N4CCCCC4)nc32)cc1 -
2-(1-methyl-2,3-dihydroindol-7-yl)-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7H-purin-8-one PubChem CID 129139957
CN1CCc2cccc(-c3ncc4[nH]c(=O)n(Cc5ccc(-c6nc(C(F)(F)F)cn6C)cc5)c4n3)c21 -
2-[2-[(1S)-1-methoxyethyl]phenyl]-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7H-purin-8-one PubChem CID 129139968
CO[C@@H](C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C)cc3)c2n1 -
2-[2-[(1R)-1-methoxyethyl]phenyl]-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7H-purin-8-one PubChem CID 129140001
CO[C@H](C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C)cc3)c2n1 -
2-[2-(4-methylpiperazin-1-yl)pyridin-3-yl]-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7H-purin-8-one PubChem CID 129140040
CN1CCN(c2ncccc2-c2ncc3[nH]c(=O)n(Cc4ccc(-c5nc(C(F)(F)F)cn5C)cc4)c3n2)CC1 -
9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-[2-[4-(trifluoromethyl)piperidin-1-yl]pyridin-3-yl]-7H-purin-8-one PubChem CID 129140066
Cn1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)[nH]c3cnc(-c4cccnc4N4CCC(C(F)(F)F)CC4)nc32)cc1 -
7-Methyl-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-[2-[3-(trifluoromethyl)azetidin-1-yl]pyridin-3-yl]purin-8-one PubChem CID 129140103
Cn1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)n(C)c3cnc(-c4cccnc4N4CC(C(F)(F)F)C4)nc32)cc1 -
9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-(2-pyrrolidin-1-ylpyridin-3-yl)-7H-purin-8-one PubChem CID 129140243
Cn1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)[nH]c3cnc(-c4cccnc4N4CCCC4)nc32)cc1 -
9-[[4-[1-(azetidin-3-yl)-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-2-(2-propan-2-ylphenyl)-7H-purin-8-one PubChem CID 129139466
CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C4CNC4)cc3)c2n1 -
2-[2-(1-hydroxyethyl)phenyl]-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7H-purin-8-one PubChem CID 129139488
CC(O)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(-c4nc(C(F)(F)F)cn4C)cc3)c2n1 -
2-[2-(1-hydroxycyclopropyl)phenyl]-9-[[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]-7H-purin-8-one PubChem CID 129139568
Cn1cc(C(F)(F)F)nc1-c1ccc(Cn2c(=O)[nH]c3cnc(-c4ccccc4C4(O)CC4)nc32)cc1 -
2-(2,2-difluoro-1,3-benzodioxol-4-yl)-9-[(4-pyrazol-1-ylphenyl)methyl]-7H-purin-8-one PubChem CID 129139668
O=c1[nH]c2cnc(-c3cccc4c3OC(F)(F)O4)nc2n1Cc1ccc(-n2cccn2)cc1