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US10072026, Example 5-9 PubChem CID 136214659
COc1ccc2c(NC3C[C@H]4CC[C@@H](C3)N4S(C)(=O)=O)nc(NC3CC(C)NN3)cc2n1 -
2-(Dimethylamino)-1-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-9-azabicyclo[3.3.1]nonan-9-yl)ethan-1-one PubChem CID 136214505
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4C(=O)CN(C)C)n2)NN1 -
1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-9-azabicyclo[3.3.1]nonan-9-yl)sulfonyl)azetidine-3-carbonitrile PubChem CID 136214512
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4S(=O)(=O)N3CC(C#N)C3)n2)NN1 -
N5-((1R,3s,5S)-9-((5-fluoropyridin-3-yl)sulfonyl)-9-azabicyclo[3.3.1]nonan-3-yl)-N7-(5-methyl-1H-pyrazol-3-yl)-1,6-naphthyridine-5,7-diamine PubChem CID 136214515
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4S(=O)(=O)c3cncc(F)c3)n2)NN1 -
N-methyl-2-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-9-azabicyclo[3.3.1]nonan-9-yl)acetamide PubChem CID 136214518
CNC(=O)CN1[C@@H]2CCC[C@H]1CC(Nc1nc(NC3CC(C)NN3)cc3ncccc13)C2 -
N7-(5-methyl-1H-pyrazol-3-yl)-N5-((1R,3s,5S)-9-(phenylsulfonyl)-9-azabicyclo[3.3.1]nonan-3-yl)-1,6-naphthyridine-5,7-diamine PubChem CID 136214510
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4S(=O)(=O)c3ccccc3)n2)NN1 -
N7-(5-methyl-1H-pyrazol-3-yl)-N5-((1R,3s,5S)-9-(pyridin-3-ylsulfonyl)-9-azabicyclo[3.3.1]nonan-3-yl)-1,6-naphthyridine-5,7-diamine PubChem CID 136214509
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4S(=O)(=O)c3cccnc3)n2)NN1 -
N5-((1R,3s,5S)-9-(ethylsulfonyl)-9-azabicyclo[3.3.1]nonan-3-yl)-N7-(5-methyl-1H-pyrazol-3-yl)-1,6-naphthyridine-5,7-diamine PubChem CID 136214511
CCS(=O)(=O)N1[C@@H]2CCC[C@H]1CC(Nc1nc(NC3CC(C)NN3)cc3ncccc13)C2