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Step 1; ethyl 6-(pyrimidin-5-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (Intermediate 16) PubChem CID 165142855
CN1CCN(Cc2cc(NC(=O)c3csc4c3CCN(c3cncnc3)C4)cc(C(F)(F)F)c2)CC1