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Found 30 results for US11046686, Example 2

N-((1r,4r)-4-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl)cyclohexyl)acetamide (Example 24) PubChem CID 146441323

CC(=O)NC1CCC(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC(C)C)s2)CC1
N-((1R,4r)-4-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (((1r,4R)-4-(5- (difluoromethyl)-1,3,4- oxadiazol-2-yl) cyclohexyl)amino)pyridin- 3-yl)-1,3,4-thiadiazol-2- yl)cy clohexyl)acetamide PubChem CID 146441426

CC(=O)NC1CCC(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC3CCC(c4nnc(C(F)F)o4)CC3)s2)CC1
methyl (((1R,3r)- 3-((5-(5- ((1r,4R)-4- acetamidocyclohexyl)- 1,3,4-thiadiazol- 2-yl)-2-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl) pyridin-4- yl)amino)cyclobutyl) methyl)carbamate PubChem CID 153459355

COC(=O)NCC1CC(Nc2cc(-c3ccc4cc(C#N)cnn34)ncc2-c2nnc(C3CCC(NC(C)=O)CC3)s2)C1
7-(5-(5-(2-aminoethyl)-1,3,4-thiadiazol-2-yl)-4-(isopropylamino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile(Example 26) PubChem CID 146382452

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(CCN)s1
(S)-7-(5-(5-(3-hydroxypyrrolidine-1-carbonyl)-1,3,4-thiadiazol-2-yl)-4-(isopropylamino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile(Example 16) PubChem CID 146382226

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(C(=O)N2CC[C@H](O)C2)s1
7-(4-(isopropylamino)-5-(5-methyl-1,3,4-thiadiazol-2-yl)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile (Example 25) PubChem CID 146382312

Cc1nnc(-c2cnc(-c3ccc4cc(C#N)cnn34)cc2NC(C)C)s1
7-(4-(isopropylamino)-5-(5-(pyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile (Example 29) PubChem CID 146382333

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(N2CCCC2)s1
7-(5-(5-(hydroxymethyl)-1,3,4-thiadiazol-2-yl)-4-(isopropylamino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile (Example 5) PubChem CID 146382355

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(CO)s1
7-(4-(isopropylamino)-5-(1,3,4-thiadiazol-2-yl)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile (Example 30) PubChem CID 146382409

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nncs1
N-((1r,4r)- 4-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)- 4-(oxetan- 3-ylamino)pyridin- 3-yl)- 1,3,4-thiadiazol-2- yl)cyclohexyl) acetamide PubChem CID 146441339

CC(=O)NC1CCC(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC3COC3)s2)CC1
N-((1r,4r)- 4-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin- 7-yl)-4- (methylamino) pyridin-3-yl)- 1,3,4-thiadiazol-2- yl)cyclohexyl) acetamide PubChem CID 146441357

CNc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(C2CCC(NC(C)=O)CC2)s1
N-((1r,4r)-4-(5-(4- ((cyanomethyl) amino)-6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl) pyridin-3- yl)-1,3,4-thiadiazol-2- yl)cyclohexyl) acetamide PubChem CID 146441580

CC(=O)NC1CCC(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NCC#N)s2)CC1
N-(1-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl)piperidin-4-yl)acetamide(Example 6) PubChem CID 146382288

CC(=O)NC1CCN(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC(C)C)s2)CC1
N-((1r,4r)-4-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-((3- methyloxetan-3- yl)amino)pyridin-3-yl)- 1,3,4-thiadiazol-2- yl)cyclohexyl)acetamide PubChem CID 146441614

CC(=O)NC1CCC(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC3(C)COC3)s2)CC1
(R)-7-(5-(5-((2- fluoro-3-hydroxy-3- methylbutyl)amino)- 1,3,4-thiadiazol-2- yl)-4- (isopropylamino) pyridin-2-yl) pyrrolo[1,2- b]pyridazine-3- carbonitrile PubChem CID 146393652

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(NC[C@@H](F)C(C)(C)O)s1
7-(5-(5-(2-oxa-7- azaspiro[3.5]nonan-7-yl)- 1,3,4-thiadiazol-2-yl)-4- (isopropylamino)pyridin- 2-yl)pyrrolo[1,2- b]pyridazine-3-carbonitrile PubChem CID 146441561

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(N2CCC3(CC2)COC3)s1
7-(5-(5-(3-hydroxy-3-methylbutyl)-1,3,4-thiadiazol-2-yl)-4-(isopropylamino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile PubChem CID 146382445

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(CCC(C)(C)O)s1
tert-butyl (2-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (isopropylamino)pyridin- 3-yl)-1,3,4-thiadiazol-2- yl)ethyl)carbamate PubChem CID 146393486

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(CCNC(=O)OC(C)(C)C)s1
(R)-5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (isopropylamino)pyridin- 3-yl)-N-(2-fluoro-3- hydroxy-3- methylbutyl)-1,3,4- thiadiazole-2- carboxamide PubChem CID 146441321

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(C(=O)NCC(F)C(C)(C)O)s1
7-(5-(5-(4- aminophenyl)-1,3,4- thiadiazol-2-yl)-4- (isopropylamino)pyridin- 2-yl)pyrrolo[1,2- b]pyridazine-3- carbonitrile PubChem CID 146441507

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(-c2ccc(N)cc2)s1