Example 4-3 - Compound Search

US9670208, Example 131 4-(3-(piperidin-3-yl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)-N-(tetrahydro-2H-pyran PubChem CID 118216796

c1cc(-c2ccn3c(C4CCCNC4)nnc3c2)nc(NC2CCOCC2)n1

US9670210, Example 59 3-{[1-(3-methoxybenzyl)-4-({[(1R,2S)-2-phenylcyclopropyl]amino}methyl)piperidin PubChem CID 118302829

COc1cccc(CN2CCC(CN[C@@H]3CC3c3ccccc3)(Cc3cccc(C(=O)O)c3)CC2)c1

US9670210, Example 107 3-(3-{[4-(methoxymethyl)-4-({[(1R,2S)-2-phenylcyclopropyl]amino}methyl)piperidin PubChem CID 118302854

COCC1(CN[C@@H]2CC2c2ccccc2)CCN(C(=O)c2ccn(CCC#N)n2)CC1

Example 19 (1-ethyl-3-{4-[4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin PubChem CID 122442117

CCNC(=O)Nc1cc(-c2[nH]c3c(c2Nc2ccccc2)C(=O)NCC3)ccn1

Example 18 (2-(3-fluoropyridin-4-yl)-3-(phenylamino)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one PubChem CID 122452996

O=C1NCCc2[nH]c(-c3ccncc3F)c(Nc3ccccc3)c21

Synthesis of 4-(3-(3,5-difluoro-4-methoxyphenyl)-6-(3-methoxypropyl)pyrazin-2-yl)benzoic Acid (Example PubChem CID 138532294

CCCCc1cnc(-c2ccc(OC)cc2)c(-c2ccc(C(=O)O)cc2)n1

Synthesis of 4-(2-(4-methoxyphenyl)-5-(3-methoxypropyl)pyridin-3-yl)benzoic Acid (Example 84) PubChem CID 138532295

CCCCc1cnc(-c2ccc(OC)cc2F)c(-c2ccc(C(=O)O)cc2)n1

Alternative Production Method of 4-(3-(3,5-difluoro-4-methoxyphenyl)-6-(3-methoxypropyl)pyrazin-2-yl) PubChem CID 138532296

CCCCc1cnc(-c2ccc(OC)cc2)c(-c2ccc(C(=O)O)c(OC)c2)n1

Synthesis of 4-(2-(4-methoxyphenyl)-5-(3-methoxypropyl)pyridin-3-yl)-2-methylbenzoic Acid (Example 116 PubChem CID 138532297

CCCCc1cnc(-c2ccc(OC)cc2)c(-c2ccc(C(=O)O)cc2C)n1

(2R,5R)-tert-butyl 5- (cyanomethyl)-5-(3-((4- (methylsulfonyl)phenyl) amino)-4-oxo-4,5- dihydro-1H-pyrazolo PubChem CID 146011760

CC(C)(C)OC(=O)[C@H]1CC[C@](CC#N)(N2NC(=Nc3ccc(S(C)(=O)=O)cc3)C3C(=O)N=CC=C32)CO1

N-(1-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl PubChem CID 146382288

CC(=O)NC1CCN(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC(C)C)s2)CC1

N-(1-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl PubChem CID 146382432

CC(=O)NC12CCC(c3nnc(-c4cnc(-c5ccc6cc(C#N)cnn56)cc4NC(C)C)s3)(CC1)OC2

(R)-N-(4-(5-(4-((1-cyanoethyl)amino)-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)pyridin-3-yl)-1,3,4-thiadiazol PubChem CID 146382475

CC(=O)NC12CCC(c3nnc(-c4cnc(-c5ccc6cc(C#N)cnn56)cc4N[C@H](C)C#N)s3)(CC1)CC2

N-(1-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl PubChem CID 146393504

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc([C@@H]2CC[C@H]2C(C)(C)O)s1

N-((1R,4r)-4-(5-(4-(((R)-1-cyanoethyl)amino)-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)pyridin-3-yl)-1,3,4 PubChem CID 146393540

CC(=O)NC1CCC(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3N[C@H](C)C#N)s2)CC1

N-((1r,4r)-4-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol PubChem CID 146441323

CC(=O)NC1CCC(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC(C)C)s2)CC1

Example 104: 4-([(1S,2S)-2-[(R)-3-Aminopiperidin-1-yl]-1,6-dichloro-2,3-dihydro-1H-inden-1-yl]oxy)-N- PubChem CID 153283863

N[C@@H]1CCCN([C@H]2Cc3c(Cl)cc(Cl)cc3[C@@H]2Oc2ccc(S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)c3ccc(O[C@H]4c5cc(Cl)cc(Cl)c5C[C@@H]4N4CCC[C@@H](N)C4)cc3Cl)c(Cl)c2)C1

N-[(3,4- Dichlorophenyl)methyl]-N- methyl-2-(4-oxo-6-piperidin-4- ylquinazolin-3-yl)acetamide (Example PubChem CID 155818433

CC(C)[C@@H](O)C(=O)N1CCC(C2CCC3NCN(CC(=O)N(C)Cc4ccc(Cl)c(Cl)c4)C(=O)C3C2)CC1

N-[(3,4- Dichlorophenyl)methyl]-N- methyl-2-(4-oxo-6-piperidin-4- ylquinazolin-3-yl)acetamide (Example PubChem CID 155818434

CC(C)[C@H](O)C(=O)N1CCC(C2CCC3NCN(CC(=O)N(C)Cc4ccc(Cl)c(Cl)c4)C(=O)C3C2)CC1

N-[(3,4- Dichlorophenyl)methyl]-N- methyl-2-(4-oxo-6-piperidin-4- ylquinazolin-3-yl)acetamide (Example PubChem CID 155818446

CN(Cc1ccc(Cl)c(Cl)c1)C(=O)CN1CNC2CCC(C3CCN(C(=O)C4CCOC4)CC3)CC2C1=O

Compound Database