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5-cyano-N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)thiophene-2-sulfonamide (Example 21) and 5 PubChem CID 176509319
CCN(C(C)c1ccc(F)cc1)S(=O)(=O)c1ccc(C#N)s1 -
(S)-N-ethyl-6-methyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)pyridine-2-sulfonamide (Example 32) and PubChem CID 176509323
Cc1cccc(S(=O)(=O)N(C)C(c2ccc(F)cc2)C(F)(F)F)n1 -
5-Cyano-N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)thiazole-2-sulfonamide (Example 80) and N-ethyl-N PubChem CID 176509339
CCN(C(C)c1ccc(F)cc1)S(=O)(=O)c1ncc(C#N)s1 -
(S)-5-Cyano-N-ethyl-N-(2,2,2-trifluoro-1-(4-(trifluoromethoxy)phenyl)ethyl)pyridine-3-sulfonamide (Example PubChem CID 176509349
CCN([C@H](C)c1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1cncc(C#N)c1 -
(R)-N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)imidazo[1,2-a]pyridine-2-sulfonamide (Example PubChem CID 176509360
CCN([C@@H](C)c1ccc(F)cc1)S(=O)(=O)c1cn2ccccc2n1 -
(R)-N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)imidazo[1,2-a]pyridine-3-sulfonamide (Example PubChem CID 176509393
CCN([C@@H](C)c1ccc(Cl)cc1)S(=O)(=O)c1cnc2ccccn12 -
(R)-N-(1-(4-chlorophenyl)-2,2,2-trifluoroethyl)-N-methylimidazo[1,2-a]pyrazine-2-sulfonamide (Example PubChem CID 176509401
C[C@@H](c1ccc(Cl)cc1)N(C)S(=O)(=O)c1cn2ccncc2n1 -
(R)-N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)imidazo[1,2-a]pyrazine-6-sulfonamide (Example PubChem CID 176509404
CCN([C@@H](C)c1ccc(F)cc1)S(=O)(=O)c1cn2ccnc2cn1 -
(S)-N-ethyl-5-fluoro-N-(2,2,2-trifluoro-1-(4-methoxyphenyl)ethyl)pyridine-3-sulfonamide (Example 256) PubChem CID 176509425
CCN([C@H](C)c1ccc(OC)cc1)S(=O)(=O)c1cncc(F)c1 -
(R)-5-cyano-N-ethyl-N-(2,2,2-trifluoro-1-(3-methyl-4-(trifluoromethyl)phenyl)ethyl)pyridine-3-sulfonamide PubChem CID 176509428
CCN([C@@H](C)c1ccc(C(F)(F)F)c(C)c1)S(=O)(=O)c1cncc(C#N)c1 -
(R)-5-fluoro-N-methyl-N-(2,2,2-trifluoro-1-(3-methyl-4-(trifluoromethyl)phenyl)ethyl)pyridine-3-sulfonamide PubChem CID 176509430
Cc1cc([C@H](C)N(C)S(=O)(=O)c2cncc(F)c2)ccc1C(F)(F)F -
Preparation of 6-((1-(cyclobutanecarbonyl)piperidine-4-yl)amino)-2-(pyrrolidin-1-yl)pyrimidine-4-carboxylic PubChem CID 176799693
CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3cccc(F)c3)n2)CC1 -
Preparation of 6-((1-(tetrahydro-2H-pyran-4-carbonyl)piperidine-4-yl)amino)pyrimidine-4-carboxylic acid PubChem CID 177373201
COC1CC(Nc2cc(C(=O)N3CCC(N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3ccccc3)n2)C1 -
Preparation of 2-isopropoxy-6-((1-(pyrimidine-4-yl)piperidine-4-yl)amino)pyrimidine-4-carboxylic acid PubChem CID 177373205
CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3cccs3)n2)CC1 -
Preparation of ((3R,4R)-4-(3,4-dihydroisoquinoline-2(1H)-yl)-3-hydroxypiperidine-1-yl)(2-isopropoxy-6 PubChem CID 177373208
CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3ccc(F)c(F)c3)n2)CC1 -
3-{[4-methylmorpholin-2-yl]methoxy}-5-(5-methyl-1,3-thiazol-2-yl)-N-{(1R)-1-[2-(trifluoromethyl)pyrimidin PubChem CID 121397299
Cc1cnc(-c2cc(OCC3CN(C)CCO3)cc(C(=O)N[C@H](C)c3cnc(C(F)(F)F)nc3)c2)s1 -
Preparation of 4-[2-methyl-2-[3-(triazol-2-yl)cyclobutyl]propanoyl]-3,5-dihydro-2H-pyrido[3,4-f][1,4] PubChem CID 135383109
CC(C)(C(=O)N1CCOc2c(C#N)cncc2C1)C1CC(OS(C)(=O)=O)C1 -
Preparation of 6-((1-acetylpiperidin-4-yl)amino)-2-(benzo[d]oxazol-7-yl)pyrimidine-4-carboxylic acid PubChem CID 166070878
CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3cccc4ncsc34)n2)CC1 -
Preparation of 6-((1-acetylpiperidine-4-yl)amino)-2-(trifluoromethoxy)pyrimidine-4-carboxylic acid (for PubChem CID 176799643
CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@H](N4CCc5ccccc5C4)[C@@H](O)C3)nc(-c3ccccc3F)n2)CC1 -
Preparation of 6-((1-acetylpiperidin-4-yl)amino)-2-vinylpyrimidine-4-carboxylic acid (for example this PubChem CID 177373195
CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3cccc4sccc34)n2)CC1