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US10072026, Example 5-38 PubChem CID 136214687
CC(C)CN1[C@@H]2CC[C@H]1CC(Nc1nc(NC3CC(C)NN3)cc3nc(CN4CCN(C)CC4)ccc13)C2 -
US10072026, Example 5-39 PubChem CID 136214688
CC1CC(Nc2cc3nc(CN4CCN(C)CC4)ccc3c(NC3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)N3CCC3)n2)NN1 -
US10072026, Example 5-40 PubChem CID 136214689
CC1CC(Nc2cc3nc(CN4CCN(C)CC4)ccc3c(NC3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)c3cncc(F)c3)n2)NN1 -
US10072026, Example 5-41 PubChem CID 136214690
CC1CC(Nc2cc3nc(CS(C)(=O)=O)ccc3c(NC3C[C@H]4CC[C@@H](C3)N4CCF)n2)NN1 -
US10072026, Example 5-42 PubChem CID 136214691
CC1CC(Nc2cc3nc(CS(C)(=O)=O)ccc3c(NC3C[C@H]4CC[C@@H](C3)N4CCCF)n2)NN1 -
US10072026, Example 5-43 PubChem CID 136214692
CC1CC(Nc2cc3nc(CS(C)(=O)=O)ccc3c(NC3C[C@H]4CC[C@@H](C3)N4CCC(F)(F)F)n2)NN1 -
US10072026, Example 6-5 PubChem CID 136214697
Cc1cnc2cc(NC3CC(C)NN3)nc(NC3C[C@H]4CC[C@@H](C3)N4S(C)(=O)=O)c2c1 -
US10072026, Example 7-5 PubChem CID 136214753
COc1ccnc2cc(NC3CC(C)NN3)nc(NC3C[C@H]4CC[C@@H](C3)N4C(=O)C(F)F)c12 -
US10072026, Example 8-5 PubChem CID 136214763
CC1CC(Nc2nc(NC3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)c3cncc(F)c3)c3cccnc3c2F)NN1 -
2,2-difluoro-1-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)ethan-1-one PubChem CID 136214506
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CC[C@@H](C3)N4C(=O)C(F)F)n2)NN1 -
Methyl 7-((5-methyl-1H-pyrazol-3-yl)amino)-5-(((1R,3s,5S)-8-(2-oxotetrahydro-2H-pyran-3-yl)-8-azabicyclo[3.2.1]octan-3-yl)amino)-1,6-naphthyridine-3-carboxylate PubChem CID 136214517
COC(=O)c1cnc2cc(NC3CC(C)NN3)nc(NC3C[C@H]4CC[C@@H](C3)N4C3CCCOC3=O)c2c1 -
N5-((1R,3s,5S)-8-((2-methoxyethyl)sulfonyl)-8-azabicyclo[3.2.1]octan-3-yl)-N7-(5-methyl-1H-pyrazol-3-yl)-1,6-naphthyridine-5,7-diamine PubChem CID 136214507
COCCS(=O)(=O)N1[C@@H]2CC[C@H]1CC(Nc1nc(NC3CC(C)NN3)cc3ncccc13)C2 -
3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile PubChem CID 136214502
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CC[C@@H](C3)N4CCC#N)n2)NN1 -
2-(Dimethylamino)-1-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-9-azabicyclo[3.3.1]nonan-9-yl)ethan-1-one PubChem CID 136214505
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4C(=O)CN(C)C)n2)NN1 -
1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-9-azabicyclo[3.3.1]nonan-9-yl)sulfonyl)azetidine-3-carbonitrile PubChem CID 136214512
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4S(=O)(=O)N3CC(C#N)C3)n2)NN1 -
Isobutyl(1R,3s,5S)-3-((2-(hydroxymethyl)-7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octane-8-carboxylate PubChem CID 136214513
CC(C)COC(=O)N1[C@@H]2CC[C@H]1CC(Nc1nc(NC3CC(C)NN3)cc3nc(CO)ccc13)C2 -
1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)sulfonyl)azetidine-3-carbonitrile PubChem CID 136214514
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)N3CC(C#N)C3)n2)NN1 -
N5-((1R,3s,5S)-9-((5-fluoropyridin-3-yl)sulfonyl)-9-azabicyclo[3.3.1]nonan-3-yl)-N7-(5-methyl-1H-pyrazol-3-yl)-1,6-naphthyridine-5,7-diamine PubChem CID 136214515
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CCC[C@@H](C3)N4S(=O)(=O)c3cncc(F)c3)n2)NN1 -
N-methyl-2-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-9-azabicyclo[3.3.1]nonan-9-yl)acetamide PubChem CID 136214518
CNC(=O)CN1[C@@H]2CCC[C@H]1CC(Nc1nc(NC3CC(C)NN3)cc3ncccc13)C2 -
N5-((1R,3s,5S)-8-(2-fluoroethyl)-8-azabicyclo[3.2.1]octan-3-yl)-N7-(5-methyl-1H-pyrazol-3-yl)-1,6-naphthyridine-5,7-diamine PubChem CID 136214503
CC1CC(Nc2cc3ncccc3c(NC3C[C@H]4CC[C@@H](C3)N4CCF)n2)NN1