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Preparation of 6-((1-(tetrahydro-2H-pyran-4-carbonyl)piperidine-4-yl)amino)pyrimidine-4-carboxylic acid (for example this intermediate could be used as an intermediate for the compound of Example 157) PubChem CID 177373201

COC1CC(Nc2cc(C(=O)N3CCC(N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3ccccc3)n2)C1