Example+6-6 - 化合物搜索

Example 12-A. tert-Butyl 4-(4-((7-(6-(4-(ethoxycarbonyl)-6-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin- PubChem CID 130211485

CCOC(=O)c1cnn(-c2cccc(-c3cccc4c3N(Cc3ccc(C5CCN(C(=O)OC(C)(C)C)CC5)cc3)CC4)n2)c1C(F)(F)F

Example 13-A. tert-Butyl 4-(4-((7-(6-(4-(ethoxycarbonyl)-6-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin- PubChem CID 130211486

CCOC(=O)c1cnn(-c2cccc(-c3cccc4c3N(Cc3ccc(C5CCN(C(=O)OC(C)(C)C)CC5)c(CC)c3)CC4)n2)c1C(F)(F)F

US10072026, Example 6-6 PubChem CID 136214698

Cc1cnc2cc(NC3CC(C)NN3)nc(NC3C[C@H]4CCC[C@@H](C3)N4CCC#N)c2c1

Example 28-A. PubChem CID 141657036

CCc1cc(Cn2cc(C)c3cccc(-c4cccc(-n5ncc(C(=O)O)c5F)n4)c32)ccc1C1CCN(C(=O)C2CC2)CC1

N-(1-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl PubChem CID 146382288

CC(=O)NC1CCN(c2nnc(-c3cnc(-c4ccc5cc(C#N)cnn45)cc3NC(C)C)s2)CC1

N-(4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)-3-methylphenyl)-6-methoxy-5-((1S,5S)-2-methyl-2,6-diazabicyclo PubChem CID 146510579

COc1ccc2ncnc(Nc3ccc(Oc4cc5ncnn5cn4)c(C)c3)c2c1N1C[C@H]2[C@@H]1CCN2C

N-[(3,4- Dichlorophenyl)methyl]-N- methyl-2-(4-oxo-6-piperidin-4- ylquinazolin-3-yl)acetamide (Example PubChem CID 155818431

CO[C@H](C)C(=O)N1CCC(C2CCC3NCN(CC(=O)N(C)Cc4ccc(Cl)c(Cl)c4)C(=O)C3C2)CC1

N-[(3,4- Dichlorophenyl)methyl]-N- methyl-2-(4-oxo-6-piperidin-4- ylquinazolin-3-yl)acetamide (Example PubChem CID 155818432

CO[C@@H](C)C(=O)N1CCC(C2CCC3NCN(CC(=O)N(C)Cc4ccc(Cl)c(Cl)c4)C(=O)C3C2)CC1

N-[(3,4- Dichlorophenyl)methyl]-N- methyl-2-(4-oxo-6-piperidin-4- ylquinazolin-3-yl)acetamide (Example PubChem CID 155818433

CC(C)[C@@H](O)C(=O)N1CCC(C2CCC3NCN(CC(=O)N(C)Cc4ccc(Cl)c(Cl)c4)C(=O)C3C2)CC1

N-[(3,4- Dichlorophenyl)methyl]-N- methyl-2-(4-oxo-6-piperidin-4- ylquinazolin-3-yl)acetamide (Example PubChem CID 155818436

CN(Cc1ccc(Cl)c(Cl)c1)C(=O)CN1CNC2CCC(C3CCN(C(=O)C(C)(C)O)CC3)CC2C1=O

US11702418, Example 6-6 PubChem CID 156526773

CNCc1c(F)cccc1-c1ccc([C@@H](C)Nc2nnc(C)c3ccc(N4CCOCC4)cc23)s1

2-(6-((6-bromo-1H- benzo[d]imidazol-1- yl)methyl)pyridin-3-yl)-5- (difluoromethyl)-1,3,4- oxadiazole PubChem CID 162767598

FC(F)c1nnc(-c2ccc(Cn3cnc4ccc(Br)cc43)nc2)o1

2-(2-chloro-6-fluoro-phenyl)-1- [(1S,3R)-6-fluoro-3-(hydroxymethyl)- 5-(3-hydroxy-3-methyl-butyl)-1- PubChem CID 163241889

C[C@H]1c2ccc(F)c(CCC(C)(C)O)c2C[C@H](CO)N1C(=O)Cc1c(F)cccc1Cl

Example 123: 4-([(1S,2S)-6-Chloro-4-cyano-2-(piperazin-1-yl)-2,3-dihydro-1H-inden-1-yl]oxy)-N-[1-(20- PubChem CID 163407733

N#Cc1cc(Cl)cc2c1C[C@H](N1CCNCC1)[C@H]2Oc1ccc(S(=O)(=O)NC2CCN(CCOCCNC(=O)NCCCCNC(=O)NCCOCCN3CCC(NS(=O)(=O)c4ccc(O[C@H]5c6cc(Cl)cc(C#N)c6C[C@@H]5N5CCNCC5)cc4)CC3)CC2)cc1

N-((R)-1-(3- (difluoromethyl)-2-fluorophenyl)ethyl)-4-(((1R5S,6s)-3-methyl-3-azabicyclo[3.1.0]hexan-6- PubChem CID 169126804

C[C@@H](NC(=O)c1cn([C@@H]2C[C@H]2C2CC2)c(=O)cc1NC1[C@H]2CN(C)C[C@@H]12)c1cccc(C(F)F)c1F

ethyl)-1-((R)-2,2- dimethyltetrahydro-2H-pyran-4-yl)-4-(((1R,5S,6s)-3-methyl-3-azabicyclo[3.1.0]hexan-6- PubChem CID 169126825

C[C@@H](NC(=O)c1cn([C@@H]2CCOC(C)(C)C2)c(=O)cc1NC1[C@H]2CN(C)C[C@@H]12)c1cccc(C(F)F)c1F

-((R)-1-(3- (difluoromethyl)-2-fluorophenyl)ethyl)-4-(((1R,5S,6s)-3-methyl-3-azabicyclo[3.1.0]hexan-6- PubChem CID 169126853

C[C@@H](NC(=O)c1cn([C@]2(C3CC3)CCOC2)c(=O)cc1NC1[C@H]2CN(C)C[C@@H]12)c1cccc(C(F)F)c1F

trifluoroethyl)-1-(1-(difluoromethyl)cyclopropyl)-4-(((1R,5S,6s)-3-methyl-3- azabicyclo[3.1.0]hexan-6- PubChem CID 169127024

CN1C[C@@H]2C(Nc3cc(=O)n(C4(C(F)F)CC4)cc3C(=O)N[C@H](c3cccc(C(F)F)c3F)C(F)(F)F)[C@@H]2C1

difluoroethyl)-1-(1-(difluoromethyl)cyclopropyl)-4-(((1R,5S,6s)-3-methyl-3- azabicyclo[3.1.0]hexan-6- PubChem CID 169321681

CN1C[C@@H]2C(Nc3cc(=O)n(C4(C(F)F)CC4)cc3C(=O)N[C@@H](c3cccc(C(F)F)c3F)C(F)F)[C@@H]2C1

N-((R)-1-(3- (difluoromethyl)-2-fluorophenyl)ethyl)-4-(((1R5S,6s)-3-methyl-3-azabicyclo[3.1.0]hexan-6- PubChem CID 169321725

C[C@@H](NC(=O)c1cn([C@H]2C[C@@H]2C2CC2)c(=O)cc1NC1[C@H]2CN(C)C[C@@H]12)c1cccc(C(F)F)c1F

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