Example+3-1 - 化合物搜索

3-{[4-methylmorpholin-2-yl]methoxy}-5-(5-methyl-1,3-thiazol-2-yl)-N-{(1R)-1-[2-(trifluoromethyl)pyrimidin PubChem CID 121397299

Cc1cnc(-c2cc(OCC3CN(C)CCO3)cc(C(=O)N[C@H](C)c3cnc(C(F)(F)F)nc3)c2)s1

3-(5-Methyl-1,3-thiazol-2-yl)-5-[morpholin-2-ylmethoxy]-N-{(1R)-1-[2-(trifluoromethyl)pyrimidin-5-yl] PubChem CID 121397625

Cc1cnc(-c2cc(OCC3CNCCO3)cc(C(=O)N[C@H](C)c3cnc(C(F)(F)F)nc3)c2)s1

(R)-3-chloro-N-methyl-N-(2,2,2-trifluoro-1-(4-(trifluoromethyl)phenyl)ethyl)imidazo[1,2-a]pyridine-6- PubChem CID 169795021

CN(C(c1ccc(C(F)(F)F)cc1)C(F)(F)F)S(=O)(=O)c1ccc2ncc(Cl)n2c1

(R)-N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)imidazo[1,2-a]pyridine-2-sulfonamide (Example PubChem CID 176509360

CCN([C@@H](C)c1ccc(F)cc1)S(=O)(=O)c1cn2ccccc2n1

Preparation of trans-(1-(6-((1-acetylpiperidine-4-yl)amino)pyrimidine-4-carbonyl)-4-(3,4-dihydroisoquinoline PubChem CID 177373199

CCNc1cc(C(=O)N2CCC(N3CCc4ccccc4C3)[C@H](O)C2)nc(-c2ccccc2)n1

Preparation of 4-[2-methyl-2-[3-(triazol-2-yl)cyclobutyl]propanoyl]-3,5-dihydro-2H-pyrido[3,4-f][1,4] PubChem CID 135383109

CC(C)(C(=O)N1CCOc2c(C#N)cncc2C1)C1CC(OS(C)(=O)=O)C1

C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(C(=O)O)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12

Preparation of 2-(pentan-3-yloxy)-6-((1-(thiazole-2-yl)piperidine-4-yl)amino)pyrimidine-4-carboxylic PubChem CID 177373207

CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3cccc(F)c3F)n2)CC1

Preparation of ((3R,4R)-4-(3,4-dihydroisoquinoline-2(1H)-yl)-3-hydroxypiperidine-1-yl)(2-isopropoxy-6 PubChem CID 177373208

CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3ccc(F)c(F)c3)n2)CC1

N-((R)-1-(3-(difluoromethyl)-2-fluorophenyl)ethyl)-1x-((S)-1- (1-fluorocyclopropane-1-carbonyl)-3-methylpyrrolidin PubChem CID 169127045

C[C@@H](NC(=O)c1cn([C@@]2(C)CCN(C(=O)C3(F)CC3)C2)c(=O)cc1NC1CCN(C)CC1)c1cccc(C(F)F)c1F

1-((S)-1-acetyl-3-methylpyrrolidin-3-yl)-N-((R)-1-(3- (difluoromethyl)-2-fluorophenyl)ethyl)-4-((1-methylpiperidin PubChem CID 169126903

CC(=O)N1CC[C@](C)(n2cc(C(=O)N[C@H](C)c3cccc(C(F)F)c3F)c(NC3CCN(C)CC3)cc2=O)C1

1-((S)-1-acetyl-3-methylpyrrolidin-3-yl)-N-((R)-1-(3- (difluoromethyl)-2-fluorophenyl)ethyl)-4-((1-methylpiperidin PubChem CID 169126992

CC(=O)N1CC[C@@](C)(n2cc(C(=O)N[C@H](C)c3cccc(C(F)F)c3F)c(NC3CCN(C)CC3)cc2=O)C1

Example 78: 3-[2-(2-[2-[(4-[[(1S,2S)-4,6-Dichloro-2-[(3R)-3-[methyl(propan-2-yl)amino]piperidin-1-yl] PubChem CID 156403359

CC(C)N(C)[C@@H]1CCCN([C@H]2Cc3c(Cl)cc(Cl)cc3[C@@H]2Oc2ccc(S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)c3ccc(O[C@H]4c5cc(Cl)cc(Cl)c5C[C@@H]4N4CCC[C@@H](N(C)C(C)C)C4)cc3)cc2)C1

N-((S)-1-(3-(difluoromethyl)-2-fluorophenyl)-2,2,2- trifluoroethyl)-1-(1-(difluoromethyl)cyclopropyl) PubChem CID 169127024

CN1C[C@@H]2C(Nc3cc(=O)n(C4(C(F)F)CC4)cc3C(=O)N[C@H](c3cccc(C(F)F)c3F)C(F)(F)F)[C@@H]2C1

N-((S)-1-(3-(difluoromethyl)-2-fluorophenyl)-2,2- difluoroethyl)-1-(1-(difluoromethyl)cyclopropyl)-4- PubChem CID 169321681

CN1C[C@@H]2C(Nc3cc(=O)n(C4(C(F)F)CC4)cc3C(=O)N[C@@H](c3cccc(C(F)F)c3F)C(F)F)[C@@H]2C1

N-((R)-1-(3-(difluoro(pyridin-4-yl)methyl)-2- fluorophenyl)ethyl)-1-(1-(difluoromethyl)cyclopropyl)-4 PubChem CID 169490311

C[C@@H](NC(=O)c1cn(C2(C(F)F)CC2)c(=O)cc1NC1[C@H]2CN(C)C[C@@H]12)c1cccc(C(F)(F)c2ccncc2)c1F

1-(bicyclo[1.1.1]pentan-1-yl)-N-((R)-1-(2-chloro-3- cyanophenyl)ethyl)-4-(((1R,5S,6s)-3-methyl-3-azabicyclo PubChem CID 169490313

C[C@@H](NC(=O)c1cn(C23CC(C2)C3)c(=O)cc1NC1[C@H]2CN(C)C[C@@H]12)c1cccc(C#N)c1Cl

N-((R)-1-(3-(difluoromethyl)-2-fluorophenyl)ethyl)-1-(1- (difluoromethyl)cyclopropyl)-4-(((1R,5S,8r)- PubChem CID 169490319

C[C@H](NC(=O)c1cn(C2(C(F)F)CC2)c(=O)cc1NC1[C@@H]2CC[C@H]1CN(C)C2)c1cccc(C(F)F)c1F

N-((2R,3S,4S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yl)-4-((1-methyl-1H-pyrazol-4-yl)methyl)-5-oxo-2-phenylpyrrolidin PubChem CID 154598309

Cn1cc(C[C@@H]2C(=O)N(c3ccc4c(cnn4-c4ccc(F)cc4)c3)[C@H](c3ccccc3)[C@H]2NC(=O)C2CC2)cn1

1-((R)-3-cyclopropyltetrahydrofuran-3-yl)-N-((R)-1-(3- (difluoromethyl)-2-fluorophenyl)ethyl)-4-(((1R PubChem CID 169126853

C[C@@H](NC(=O)c1cn([C@]2(C3CC3)CCOC2)c(=O)cc1NC1[C@H]2CN(C)C[C@@H]12)c1cccc(C(F)F)c1F

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