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共找到 49 条结果，关键词：US11459315, Example 4 (isomer 1)

1-((R)-1-(4-(3-cyanoazetidin-1-yl)cyclohexyl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-indole-3-carboxamide PubChem CID 166177813

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(N3CC(C#N)C3)CC2)c2ccccc12
2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-((R)-1-(4-((1-methylazetidin-3-yl)oxy)cyclohexyl)ethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide PubChem CID 166177822

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(OC3CN(C)C3)CC2)c2ncccc12
2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-((R)-1-(4-(3-(methylsulfonyl)azetidin-1-yl)cyclohexyl)ethyl)-1H-indole-3-carboxamide PubChem CID 166177839

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(N3CC(S(C)(=O)=O)C3)CC2)c2ccccc12
1-((R)-1-(4-hydroxycyclohexyl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide PubChem CID 166177711

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(O)CC2)c2ncccc12
6-fluoro-1-((R)-1-(4-hydroxycyclohexyl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-indole-3-carboxamide PubChem CID 166177719

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(O)CC2)c2cc(F)ccc12
1-((R)-1-(4-(dimethylamino)cyclohex-yl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide PubChem CID 166177726

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(N(C)C)CC2)c2ncccc12
5-chloro-1-((R)-1-(4-hydroxycyclohexyl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide PubChem CID 166177728

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(O)CC2)c2ncc(Cl)cc12
1-((R)-1-(4-(difluoromethoxy)cyclohex-yl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-indole-3-carboxamide PubChem CID 166177735

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(OC(F)F)CC2)c2ccccc12
2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-((R)-1-(4-(oxetan-3-ylamino)cyclohexyl)ethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide PubChem CID 166177737

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(NC3COC3)CC2)c2ncccc12
1-((R)-1-(4-(2-methoxyethoxy)cyclohex-yl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-indole-3-carboxamide PubChem CID 166177742

COCCOC1CCC([C@@H](C)n2c(C)c(C(=O)NCC3C(=O)N=C(C)C=C3SC)c3ccccc32)CC1
2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-((R)-1-(4-morpholinocyclohexyl)eth-yl)-1H-indole-3-carboxamide PubChem CID 166177751

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(N3CCOCC3)CC2)c2ccccc12
7-((R)-1-(4-(3-cyclopropoxyazetidin-1-yl)cyclohexyl)ethyl)-6-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide PubChem CID 166177777

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(N3CC(OC4CC4)C3)CC2)c2ncncc12
6-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7-((R)-1-(4-(3-(trifluoromethoxy)azetidin-1-yl)cyclohexyl)ethyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide PubChem CID 166177798

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(N3CC(OC(F)(F)F)C3)CC2)c2ncncc12
4-((R)-1-(2-methyl-3-(((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)-1H-indol-1-yl)ethyl)cyclohexylacetate PubChem CID 166177808

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(CC(=O)[O-])CC2)c2ccccc12
2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-((R)-1-(4-(oxetan-3-yloxy)cyclohexyl)ethyl)-1H-indole-3-carboxamide PubChem CID 166177812

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(OC3COC3)CC2)c2ccccc12
4-((R)-1-(2-methyl-3-(((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)-1H-indol-1-yl)ethyl)cyclohexylbutyrate PubChem CID 166177818

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(CCCC(=O)[O-])CC2)c2ccccc12
4-((R)-1-(2-methyl-3-(((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)-1H-indol-1-yl)ethyl)cyclohexylisobutyrate PubChem CID 166177820

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(CC(C)C(=O)[O-])CC2)c2ccccc12
2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-((1R)-1-(4-((3-methyltetrahydrofuran-3-yl)amino)cyclohexyl)ethyl)-1H-indole-3-carboxamide PubChem CID 166177826

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(NC3(C)CCOC3)CC2)c2ccccc12
1-((R)-1-(4-((3-(fluoromethyl)oxetan-3-yl)amino)cyclohexyl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide PubChem CID 166177832

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(NC3(CF)COC3)CC2)c2ncccc12
6-fluoro-1-((R)-1-(4-((3-(hydroxymethyl)oxetan-3-yl)amino)cyclohexyl)ethyl)-2-methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1H-indole-3-carboxamide PubChem CID 166177836

CSC1=CC(C)=NC(=O)C1CNC(=O)c1c(C)n([C@H](C)C2CCC(NC3(CO)COC3)CC2)c2cc(F)ccc12