Example+7-3 - 化合物搜索

(1S,3''''R,6''''R,7''''R,8''''E,11''''S,12''''R)- 6-chloro-7''''-methoxy-11,12- dimethyl-7''''-(((9aR)-8- (methylsulfonyl)octahydro-2H- pyrazino[1,2-a]pyrazin-2- yl)methyl)-3,4-dihydro- 2H,15''''H-spiro[naphthalene- 1,22''''-[20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19,24~] pentacosa[8,16,18,24]tetraen]- 15''''-one 13%13-dioxide PubChem CID 140924639

CO[C@]1(CN2CCN3CCN(S(C)(=O)=O)C[C@@H]3C2)/C=C/C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3

(1S,3''''R,6''''R,7''''S,8''''E,11''''S,12''''R)- 6-chloro-7''''-methoxy-11'''',12''''- dimethyl-7''''-(((9aR)-8-(1- methylethyl)octahydro-2H- pyrazino[1,2-a]pyrazin-2- yl)methyl)-3,4-dihydro- 2H,15''''H-spiro[naphthalene- 1,22''''-[20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19,24~] pentacosa[8,16,18,24]tetraen]- 15''''-one 13'''',13''''-dioxide PubChem CID 140924716

CO[C@@]1(CN2CCN3CCN(C(C)C)C[C@@H]3C2)/C=C/C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3

(1S,3''''R,6''''R,7''''S,8''''E,11''''S,12''''R)- 6-chloro-7''''-methoxy-11'''',12''''- dimethyl-7''''-(((9aR)-8- (methylsulfonyl)octahydro-2H- pyrazino[1,2-a]pyrazin-2- yl)methyl)-3,4-dihydro- 2H,15''''H-spiro[naphthalene- 1,22''''-[20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19,24~] pentacosa[8,16,18,24]tetraen]- 15''''-one 13'''',13''''-dioxide PubChem CID 140924724

CO[C@@]1(CN2CCN3CCN(S(C)(=O)=O)C[C@@H]3C2)/C=C/C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3

(1S,3''R,6''R,7''R,8''E,11''S,12''R)- 6-chloro-7''-hydroxy-11'',12''- dimethyl-7''-((9aR)-octahydro- 2H-pyrido[1,2-a]pyrazin-2- ylmethyl)-3,4-dihydro- 2H,15''H-spiro[naphthalene- 1,22''-[20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19,24~] pentacosa[8,16,18,24]tetraen]- 15''-one 13'',13''-dioxide PubChem CID 140924727

C[C@@H]1[C@@H](C)C/C=C/[C@@](O)(CN2CCN3CCCC[C@@H]3C2)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc43)COc3ccc(cc32)C(=O)NS1(=O)=O

(1S,3''R,6''R,7''R,8''E,11''S,12''R)- 6-chloro-7''-(((8R,9aR)-8- fluorooctahydro-2H- pyrido[1,2-a]pyrazin-2- yl)methyl)-7''-methoxy-11'',12''- dimethyl-3,4-dihydro-2H,15''H- spiro[naphthalene-1,22''- [20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19,24~] pentacosa[8,16,18,24]tetraen]- 15''-one 13'',13''-dioxide PubChem CID 140924804

CO[C@]1(CN2CCN3CC[C@H](F)C[C@@H]3C2)/C=C/C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3

(1S,3''R,6''R,7''S,8''E,11''S,12''R)- 6-chloro-7''-(((8R,9aR)-8- fluorooctahydro-2H- pyrido[1,2-a]pyrazin-2- yl)methyl)-7''-methoxy-11'',12''- dimethyl-3,4-dihydro-2H,15''H- spiro[naphthalene-1,22''- [20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19,24~] pentacosa[8,16,18,24]tetraen]- 15''-one 13'',13''-dioxide PubChem CID 140924886

CO[C@@]1(CN2CCN3CC[C@H](F)C[C@@H]3C2)/C=C/C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3

(1S,3''''R,6''''R,7''''R,8''''E,11''''S,12''''R)- 6-chloro-7''''-hydroxy-11'''',12''''- dimethyl-7''''-((9aR)-octahydro- 2H-pyrido[1,2-a]pyrazin-2- ylmethyl)-3,4-dihydro- 2H,15''''H-spiro[naphthalene- 1,22''''-[20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19,24~] pentacosa[8,16,18,24]tetraen]- 15''''-one 13'''',13''''-dioxide PubChem CID 140924972

C[C@@H]1[C@@H](C)C/C=C/[C@](O)(CN2CCN3CCCC[C@@H]3C2)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc43)COc3ccc(cc32)C(=O)NS1(=O)=O

(1S,3''''R,6''''R,7''''S,8''''E,11''''S,12''''R)- 7''''-(((9aS)-8-acetyloctahydro- 2H-pyrazino[1,2-a]pyrazin-2- yl)methyl)-6-chloro-7''''- methoxy-11'''',12''''-dimethyl-3,4- dihydro-2H,15''''H- spiro[naphthalene-1,22''''- [20]oxa[13]thia[1,14] diazatetracyclo [14.7.2.0~3,6~.0~19''''24~] pentacosa[8,16,18,24]tetraen]- 15''''-one 13'''',13''''-dioxide PubChem CID 140924981

CO[C@@]1(CN2CCN3CCN(C(C)=O)C[C@@H]3C2)/C=C/C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3

(R)-7-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazol-4-yl)phenyl)-7H-pyrrolo[1,2-a]imidazol-7-ol. PubChem CID 164607755

O[C@]1(c2cccc(-c3csc(-c4c[nH]c5nccnc45)n3)c2)Cc2nccn2C1

5-amino-3-[(5S,7R,8R,12aR,14R,15aS)-14-(4- amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,10- dihydroxy-2,10-disulfidooctahydro-12H-5,8- methanofuro[3,2- l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetra- decin-7-yl]-3,6-dihydro-7H-[1,2,3]triazolo[4,5- d]pyrimidin-7-one (Diastereomer 1) PubChem CID 166177592

N=C1N=C2C(N=NN2[C@@H]2O[C@@H]3COP(O)(=S)O[C@H]4C[C@H](n5ccc6c(N)ncnc65)O[C@@H]4COP(O)(=S)O[C@@H]2C3)C(=O)N1

5-amino-3-[(5S,7R,8R,12aR,14R,15S,15aR)-14- (4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-15- fluoro-2,10-dihydroxy-2,10-disulfidooctahydro- 12H-5,8-methanofuro[3,2- l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetra- decin-7-yl]-3,6-dihydro-7H-[1,2,3]triazolo[4,5- d]pyrimidin-7-one (Diastereomer 1) PubChem CID 166177595

N=C1N=C2C(N=NN2[C@@H]2O[C@@H]3COP(O)(=S)O[C@H]4[C@H](F)[C@H](n5ccc6c(N)ncnc65)O[C@@H]4COP(O)(=S)O[C@@H]2C3)C(=O)N1

(1r,3R)-N-((1R,5S,8s)-3-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl)-3-azabicyclo[3.2.1]octan-8-yl)-3-hydroxy-3-methylcyclobutane-1-carboxamide PubChem CID 146441318

CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(N2C[C@H]3CC[C@@H](C2)C3NC(=O)C2CC(C)(O)C2)s1

trans-N-{5-(7''-Fluoro-3''-methyl-2''- oxo-3-(pyridin-3-yl)-2'',3''- dihydrospiro[cyclobutane-1,1''-pyrrolo[2,3- c]quinolin]-8''-yl)-2-(2- (isopropylamino)ethoxy)pyridin-3- yl)methanesulfonamide PubChem CID 146211649

CC(C)NCCOc1ncc(-c2cc3c4c(cnc3cc2F)N(C)C(=O)C42CC(c3cccnc3)C2)cc1NS(C)(=O)=O

cis-N-(5-(7''-Fluoro-3-(6- methoxypyridin-3- yl))-3''-methyl-2''-oxo-2'',3''- dihydrospiro[cyclobutane-1,1''-pyrrolo[2,3- c]quinolin]-8''-yl)-2-(2- (isopropylamino)ethoxy)pyridin-3- yl)methanesulfonamide PubChem CID 146211651

COc1ccc(C2CC3(C2)C(=O)N(C)c2cnc4cc(F)c(-c5cnc(OCCNC(C)C)c(NS(C)(=O)=O)c5)cc4c23)cn1

trans-N-(5-(3-(3-Chlorophenyl)-7''- fluoro-3''-methyl-2''-oxo-2'',3''- dihydrospiro[cyclobutane-1,1''-pyrrolo[2,3- c]quinolin]-8''-yl)-2-(2- (isopropylamino)ethoxy)pyridin-3- yl)methanesulfonamide PubChem CID 146212452

CC(C)NCCOc1ncc(-c2cc3c4c(cnc3cc2F)N(C)C(=O)C42CC(c3cccc(Cl)c3)C2)cc1NS(C)(=O)=O

(3[R or S],4[S or R], 5''S,7a''R)-3-fluoro-1-(3- fluoropyrazolo[1,5-a] pyrimidin-7-yl)-5''- phenyltetrahydro-3''H- spiro[piperidine-4,2''- pyrrolo[2,1-b]oxazol]-3''- one, TFA salt PubChem CID 168244887

O=C1N2[C@@H](CC[C@H]2c2ccccc2)OC12CCN(c1ccnc3c(F)cnn13)CC2F

(1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-11',12'- dimethyl-7'-(trans-5-(methylamino)-1,3- dioxan-2-yl)-3,4-dihydro-2H,15'H- spiro[naphthalene-1,22'- [20]oxa[13]thia[1,14]diazatetracyclo [14.7.2.0~3,6~.0~19,24~]pentacosa[16,18,24] trien]-15'-one 13',13'-dioxide OR PubChem CID 142532685

CNC1COC([C@H]2CCC[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c3ccc4c(c3)N(C[C@@H]3CC[C@H]32)C[C@@]2(CCCc3cc(Cl)ccc32)CO4)OC1

(1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-11',12'- dimethyl-7'-((2r,3aR,6aS)-tetrahydro-3aH- [1,3]dioxolo[4,5-c]pyrrol-2-yl)-3,4-dihydro- 2H,15'H-spiro[naphthalene-1,22'- [20]oxa[13]thia[1,14]diazatetracyclo [14.7.2.0~3,6~.0~19,24~]pentacosa[16,18,24] trien]-15'-one 13',13'-dioxide OR PubChem CID 155640446

C[C@@H]1[C@@H](C)CCC[C@H](C2O[C@H]3CNC[C@H]3O2)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc43)COc3ccc(cc32)C(=O)NS1(=O)=O

(1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-hydroxy-1,3-dioxan-2-yl)-11',12'-dimethyl- 3,4-dihydro-2H,15'H-spiro[naphthalene-1,22'- [20]oxa[13]thia[1,14]diazatetracyclo [14.7.2.0~3,6~.0~19,24~]pentacosa[16,18,24] trien]-15'-one 13',13'-dioxide OR PubChem CID 155640449

C[C@@H]1[C@@H](C)CCC[C@H](C2OCC(O)CO2)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc43)COc3ccc(cc32)C(=O)NS1(=O)=O

5-amino-3-[(5S,7R,8R,12aR,14R,15R,15aS)-14- (6-amino-9H-purin-9-yl)-2,10-dihydroxy-2,10- disulfidohexahydro-14H-15,12a- (epoxymethano)-5,8-methanofuro[3,2- l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetra- decin-7(12H)-yl]-3,6-dihydro-7H- [1,2,3]triazolo[4,5-d]pyrimidin-7-one (Diastereomer 1) PubChem CID 166177591

N=C1N=C2C(N=NN2[C@@H]2O[C@@H]3COP(O)(=S)O[C@H]4[C@H]5OC[C@]4(COP(O)(=S)O[C@@H]2C3)O[C@H]5n2cnc3c(N)ncnc32)C(=O)N1

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