Primary Record
Tezacaftor
- In stock
- 5,987 g
- Purity
- 98.2 %
- CAS
- 1152311-62-0
Compound Identifiers & Properties
- CAS
- 1152311-62-0
- PubChem CID
- 46199646
- SMILES
- CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F
- Canonical SMILES
- CC(C)(CO)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1C[C@@H](O)CO
Names & Synonyms
- Tezacaftor
- VX-661
- 1152311-62-0
- tezacaftorum
- Tezacaftor [USAN]
- Alyftrek
- Trikafta
- Kaftrio
- Symdeko
- Symkevi
- Tezacaftor (VX-661)
- Tezacaftor; VX-661
- TEZACAFTOR [MI]
- UNII-8RW88Y506K
- TEZACAFTOR [INN]
- RefChem:897552
- Tezacaftor (USAN/INN)
- 8RW88Y506K
- MFCD23106064
- VX 661
- D0Z5HR
- C26H27F3N2O6
- TEZACAFTOR [WHO-DD]
- VX661
- SCHEMBL322362
- DTXSID40673070
- MJUVRTYWUMPBTR-MRXNPFEDSA-N
- VX 661;VX661;Tezacaftor
- orb1305866
- SYMKEVI COMPONENT TEZACAFTOR
- CHEMBL3544914
- SCHEMBL29371825
- SCHEMBL29433210
- TEZACAFTOR [ORANGE BOOK]
- TRIKAFTA COMPONENT TEZACAFTOR
- GTPL10199
- KS-00000SZM
- DTXCID00623819
- CHEBI:234517
- BDBM281054
- GLXC-90364
- (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
- AMX10192
- BCP07173
- EX-A1759
- ARD164048
- EBC-27272
- s7059
- US10022352, Compound 315
- VX661?
- ZINC68206930
- AKOS025290350
- ACN-041468
- CCG-269854
- CS-1078
- DB11712
- AC-32773
- AK172569
- AS-35211
- BC600502
- FD104056
- HY-15448
- QC-11636
- SC-95542
- SY375095
- CFTR correctors (cystic fibrosis), Vertex
- A2664
- example 315 [US20090131492A1]
- NS00072907
- SW219937-1
- Y0430
- J3.793.763K
- A12519
- D11041
- Q-4067
- cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-n-[1-[(2r)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1h-indol-5-yl]-
- EN300-7398484
- A857959
- BRD-K97101532-001-02-8
- Q27270940
- (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-
- 1-(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl}cyclopropane-1-carboxamide
- Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl)-
- B0084-463370
- 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl)cyclopropanecarboxamide
- 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
- 1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-N-{1-[(2R)-2,3-DIHYDROXYPROPYL]-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)INDOL-5-YL}CYCLOPROPANE-1-CARBOXAMIDE
- Cystic fibrosis transmembrane regulator corrector (cystic fibrosis), Vertex
- (1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
- (R)-1 (2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
- (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-[1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methyl-2-propyl)-5-indolyl]cyclopropanecarboxamide
- 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-~(N)-(1-((2~(R))-2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl)cyclopropane-1-carboxamide
- 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-~{N}-[1-[(2~{R})-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
- 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethyl-ethyl)indol-5-yl]cyclopropanecarboxamide
- 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl] -cyclopropanecarboxamide
- 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide
- 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide
- 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide (ACI); 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide; (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide; Tezacaftor; VX 661
- 1-(2,2-difluoro-1,3-dioxaindan-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl}cyclopropane-1-carboxamide
- 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
- CV6