Chemical Compound

Navitoclax

CAS Registry Number 923564-51-6
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Navitoclax chemical structure
Primary Record

Navitoclax

In stock
709 g
Purity
98.7 %
CAS
923564-51-6

Compound Identifiers & Properties

CAS
923564-51-6
PubChem CID
24978538
SMILES
CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)N[C@H](CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
Canonical SMILES
CC1(C)CCC(c2ccc(Cl)cc2)=C(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(N[C@H](CCN5CCOCC5)CSc5ccccc5)c(S(=O)(=O)C(F)(F)F)c4)cc3)CC2)C1

Names & Synonyms

  • Navitoclax
  • ABT-263
  • 923564-51-6
  • ABT 263
  • navitoclaxum
  • ABT263
  • yl)benzamide
  • ABT-263 (Navitoclax)
  • Navitoclax [USAN]
  • UNII-XKJ5VVK2WD
  • XKJ5VVK2WD
  • Navitoclax (ABT-263)
  • S1001_Selleck
  • Navitoclax [USAN:INN]
  • ABT-263 Navitoclax
  • ABT-263,Navitoclax
  • ABT263, Navitoclax
  • NAVITOCLAX [MI]
  • ABT-263 In Bulk
  • Navitoclax, ABT-263
  • Navitoclax; ABT-263
  • NAVITOCLAX [INN]
  • NAVITOCLAX [JAN]
  • C47H55ClF3N5O6S3
  • RefChem:832111
  • ABT-263 - Navitoclax
  • D06ETI
  • CHEMBL443684
  • ABT-263 (Navitoclax)?
  • NAVITOCLAX [WHO-DD]
  • DTXSID2042640
  • cc-344
  • MLS006011021
  • Navitoclax (JAN/USAN/INN)
  • SCHEMBL522847
  • CHEBI:131174
  • GTPL8319
  • orb1306480
  • DTXCID0022640
  • SCHEMBL29363785
  • CHEBI:94128
  • CTK8E8268
  • KS-00001COV
  • ABT-737
  • AOB1912
  • EX-A055
  • JLYAXFNOILIKPP-KXQOOQHDSA-N
  • MFCD12756219
  • ABT-263(Navitoclax)/ABT263
  • GLXC-02824
  • ABP000127
  • BDBM50270877
  • NSC759659
  • s1001
  • AKOS015896297
  • ZINC150338726
  • A-855071.0
  • ACN-051778
  • AN-1321
  • CB11511
  • CS-0013
  • DB12340
  • FN16901
  • NSC-759659
  • RG-7433
  • RL05817
  • NCGC00188344-01
  • NCGC00188344-02
  • NCGC00188344-03
  • NCGC00188344-05
  • NCGC00188344-08
  • 4CA-0894
  • AC-31055
  • AS-16690
  • BC660006
  • CID:24978538
  • HY-10087
  • SMR004702817
  • BcI-2 Family Protein Inhibitor ABT-263
  • SID:134221945
  • 4-[4-[[2-(4-chlorophenyl)-5,5-dimet
  • AB0008156
  • AB1010838
  • RT-011151
  • Tetradecanoic acid, 11-hydroxy-, (11R)-
  • A3007
  • A8196
  • NS00073445
  • SW218055-2
  • X7535
  • (R)-4-(4-((4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide
  • 3-(3-Methoxyphenyl)-2-nitroprop-2-en-1-ol
  • J2.623.777G
  • A10022
  • A10937
  • D09935
  • 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
  • 564A516
  • C528561
  • 4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
  • I06-2050
  • BRD-K82746043-001-01-1
  • BRD-K82746043-001-02-9
  • BRD-K82746043-001-03-7
  • BRD-K82746043-001-04-5
  • BRD-K82746043-001-15-1
  • BRD-K82746043-001-19-3
  • Q18002993
  • 3-METHYL-5H-[1,2]OXAZOLO[4,5-D]PYRIDAZIN-4-ONE
  • B0084-100624
  • (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide
  • 1-(2,4-difluorophenyl)-3-methyl-3-azabicyclo[3.1.0]hexane
  • 1-(3,4-dichlorophenyl)-3-oxabicyclo[3.1.0]hexane-2,4-dione
  • 3-butyl-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane
  • 4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-cyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(1R)-3-morpholino-1-(phenylsulfanylmethyl)propyl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonyl-benzamide
  • 1-(3,4-dichlorophenyl)-3-methyl-3-azabicyclo[3.1.0]hexan-2-one
  • 2-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]phthalazin-1-one
  • 2-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]phthalazin-1-one
  • (R)-4-(4-((2-(4-Chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)p
  • 3-methyl-7-(2-nitrophenyl)-5H-[1,2]oxazolo[4,5-d]pyridazin-4-one
  • 3-methyl-7-(4-nitrophenyl)-5H-[1,2]oxazolo[4,5-d]pyridazin-4-one
  • 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-trifluoromethanesulfonylbenzenesulfonyl)benzamide
  • 4-(4-{[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex-1-En-1-Yl]methyl}piperazin-1-Yl)-N-[(4-{[(2r)-4-(Morpholin-4-Yl)-1-(Phenylsulfanyl)butan-2-Yl]amino}-3-[(Trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide
  • 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-mo
  • 7-(2-aminophenyl)-3-methyl-5H-[1,2]oxazolo[4,5-d]pyridazin-4-one
  • ABT 263, 98%, potent inhibitor of Bcl-xL,Bcl-2 and Bcl-w - 10MG 10mg
  • Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((4-(((1R)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)-
  • N-[2-(BROMOMETHYL)-4-METHOXYPHENYL]-2,2,3,3,4,4,4-HEPTAFLUOROBUTANIMIDOYL CHLORIDE
  • (4-(((3S)-4-(((1,1-dimethylethyl)oxy)carbonyl)-3-methyl-1-piperazinyl)methyl)phenyl)acetic acid
  • (R)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfon
  • (R)-4-(4-((4-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide
  • 1093851-28-5
  • 119229-65-1
  • 1XJ
  • 4-(4-((2-(4-CHLOROPHENYL)-5,5-DIMETHYLCYCLOHEX-1-EN-1-YL)METHYL)PIPERAZIN-1-YL)-N-((4-(((2R)-4-(MORPHOLIN-4-YL)-1-(PHENYLSULFANYL)BUTAN-2-YL)AMINO)-3-((TRIFLUOROMETHYL)SULFONYL)PHENYL)SULFONYL)BENZAMIDE
  • 4-(4-((2-(4-CHLOROPHENYL)-5,5-DIMETHYLCYCLOHEX-1-EN-1-YL)METHYL)PIPERAZIN-1-YL)-N-(4-(((2R)-4-(MORPHOLIN-4-YL)-1-(PHENYLSULFANYL)BUTAN-2-YL)AMINO)-3-(TRIFLUOROMETHANESULFONYL)BENZENESULFONYL)BENZAMIDE
  • 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-(4-(((2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl)amino)-3-trifluoromethanesulfonylbenzenesulfonyl)benzamide
  • 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl)methyl)piperazin-1-yl)-N-(4-(((2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl)amino)-3-(trifluoromethylsulfonyl)phenyl)sulfonylbenzamide
  • 4-(4-{[2-(4-Chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({4-({(1R)-3-(morpholin-4-yl)-1-[(phenylsulfanyl)methyl]propyl}amino)-3-[(trifluoromethyl)sulfonyl]phenyl}sulfonyl)benzamide
  • 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({4-({(1R)-3-morpholin-4-yl-1-[(phenylsulfanyl)methyl]propyl}amino)-3-[(trifluoromethyl)sulfonyl]phenyl}sulfonyl)benzamide
  • 4-(4-{[2-(4-Chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-(trifluoromethanesulfonyl)benzene-1-sulfonyl)benzamide
  • 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-
  • 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)me
  • 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;ABT 263;Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dime
  • 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexenyl]methyl]piperazino]-N-[[4-[[(1R)-3-morpholino-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
  • 4-{4-[(4'-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro[1,1'-biphenyl]-2-yl)methyl]piperazin-1-yl}-N-[4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-(trifluoromethanesulfonyl)benzene-1-sulfonyl]benzamide
  • 4-{4-[(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro[biphenyl]-2-yl)methyl]piperazin-1-yl}-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide
  • 852808-04-9
  • 923565-16-6
  • 923565-73-5
  • 923567-58-2
  • 923567-62-8
  • 923567-66-2
  • 923567-78-6
  • 923568-35-8
  • 923569-55-5
  • 923569-56-6
  • 923569-62-4
  • 923569-69-1
  • 923569-70-4
  • 923569-71-5
  • 923569-78-2
  • ABT-263|||4-[4-[[2-(4-Chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
  • BENZAMIDE, 4-(4-((2-(4-CHLOROPHENYL)-5,5-DIMETHYL-1-CYCLOHEXEN-1-YL)METHYL)-1- PIPERAZINYL)-N-((4-(((1R)-3-(4-MORPHOLINYL)-1-((PHENYLTHIO)METHYL)PROPYL)AMINO)-3-((TRIFLUOROMETHYL)SULFONYL)PHENYL)SULFONYL)-
  • N-(4-{4-[2-(4-chlorophenyl)-5,5-dimethyl-cyclohex-1-enylmethyl]-piperazin-1-yl}-benzoyl)-4-((r)-3-morpholin-4-yl-1-phenylsulfanylmethyl-propylamino)-3-trifluoromethanesulfonyl-benzenesulfonamide
  • N-[3-(Trifluoromethylsulfonyl)-4-[[(R)-1-(phenylthiomethyl)-3-morpholinopropyl]amino]phenylsulfonyl]-4-[4-[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexenylmethyl]piperazino]benzamide