Primary Record
Murizatoclax
- In stock
- 1,355 g
- Purity
- 98.5 %
- CAS
- 2245848-05-7
Compound Identifiers & Properties
- CAS
- 2245848-05-7
- PubChem CID
- 138669688
- SMILES
- C[C@H]1C/C=C/[C@@]([C@@H]2CC[C@H]2CN3C[C@@]4(CCCC5=C4C=CC(=C5)Cl)COC6=C3C=C(C=C6)C(=O)NS(=O)(=O)[C@@H]1C)(CN7CCN8CCCC[C@@H]8C7)OC
- Canonical SMILES
- CO[C@]1(CN2CCN3CCCC[C@@H]3C2)/C=C/C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3c(c2)N(C[C@@H]2CC[C@H]21)C[C@@]1(CCCc2cc(Cl)ccc21)CO3
Names & Synonyms
- Murizatoclax
- Murizatoclax [USAN]
- MURIZATOCLAX [INN]
- AMG-397
- RefChem:160130
- MURIZATOCLAX [WHO-DD]
- AMG 397
- BO0V7196L2
- MCL-1 inhibitor AMG 397
- UNII-BO0V7196L2
- AMG397
- orb1704854
- CHEMBL4650225
- SCHEMBL21040009
- SCHEMBL29395453
- SCHEMBL30044361
- 2245848-05-7
- BDBM470606
- EX-A9783
- US10821115, Example 10
- NSC845308
- WHO 11281
- AKOS040745010
- NSC-845308
- MS-31374
- HY-109184
- CS-0116455
- Myeloid Cell Leukemia 1 Inhibitor AMG 397
- G18013
- A1020341
- Spiro(5,7-etheno-1H,11H-cyclobut(i)(1,4)oxazepino(3,4-f)(1,2,7)thiadiazacyclohexadecine-2(3H),1'(2'H)-naphthalen)-8(9H)-one, 6'-chloro-3',4',12,13,16,16a,17,18,18a,19-decahydro-16-methoxy-11,12-dimethyl-16-(((9aR)-octahydro-2H-pyrido(1,2-a)pyrazin-2-yl)methyl)-, 10,10-dioxide, (1'S,11R,12S,14E,16R,16aR,18aR)-
- (13S,31R,32R,4R,5E,8S,9R)-6'-Chloro-4-methoxy-8,9-dimethyl-4-(((9aR)-octahydro-2H-pyrido(1,2-a)pyrazin-2-yl)methyl)-3',4'-dihydro-12H,14H,2'Hspiro(10lambda6-thia-11-aza-1(5,7)-(1,5)benzoxazepina-3(1,2)-cyclobutanacyclododecaphan-5-ene-13,1'-naphthalene)-10,10,12-trione
- (13S,31R,32R,4R,5E,8S,9R)-6'-CHLORO-4-METHOXY-8,9-DIMETHYL-4-(((9AR)- OCTAHYDRO-2H-PYRIDO(1,2-A)PYRAZIN-2-YL)METHYL)-3',4'-DIHYDRO-12H,14H,2'HSPIRO( 10.LAMBDA.6-THIA-11-AZA-1(5,7)-(1,5)BENZOXAZEPINA-3(1,2)- CYCLOBUTANACYCLODODECAPHAN-5-ENE-13,1'-NAPHTHALENE)-10,10,12-TRIONE
- (13S,31R,32R,4R,5E,8S,9R)-6'-CHLORO-4-METHOXY-8,9-DIMETHYL-4-(((9AR)-OCTAHYDRO-2H-PYRIDO(1,2-A)PYRAZIN-2-YL)METHYL)-3',4'-DIHYDRO-12H,14H,2'HSPIRO(10.LAMBDA.6-THIA-11-AZA-1(5,7)-(1,5)BENZOXAZEPINA-3(1,2)-CYCLOBUTANACYCLODODECAPHAN-5-ENE-13,1'-NAPHTHALENE)-10,10,12-TRIONE
- (3'R,4S,6'R,7'R,8'E,11'S,12'R)-7'-[[(9aR)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl]methyl]-7-chloro-7'-methoxy-11',12'-dimethyl-13',13'-dioxospiro[2,3-dihydro-1H-naphthalene-4,22'-20-oxa-13
- (3'R,4S,6'R,7'R,8'E,11'S,12'R)-7'-[[(9aR)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl]methyl]-7-chloro-7'-methoxy-11',12'-dimethyl-13',13'-dioxospiro[2,3-dihydro-1H-naphthalene-4,22'-20-oxa-13|E6-thia-1,14-diazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,16(25),17,19(24)-tetraene]-15'-one
- >>6-thia-1,14-diazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,16(25),17,19(24)-tetraene]-15'-one