Chemical Compound

Aprepitant

CAS Registry Number 170729-80-3

Back to search Request a Quote

Primary Record

Aprepitant

In stock: 7,788 g
Purity: 98.3 %
CAS: 170729-80-3

Compound Identifiers & Properties

CAS: 170729-80-3
PubChem CID: 135413536
SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=C(C=C4)F
Canonical SMILES: C[C@@H](O[C@H]1OCCN(Cc2n[nH]c(=O)[nH]2)[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1

Names & Synonyms

Aprepitant
Emend
170729-80-3
Cinvanti
Aponvie
aprepitantum
Agrepitant
Apripetant
eMende
MK-869
Aprepitant [USAN]
Aprepitant CRS
Emend (TN)
Cinvanti (TN)
aprepitant, form I
Aponvie (TN)
MK-0869
aprepitant, form II
Aprepitant Impurity I
Aprepitant (Standard)
AC1OCFCG
1NF15YR6UY
ONO-7436
APREPITANT [MI]
RefChem:57104
UNII-1NF15YR6UY
Fosaprepitant Impurity C
APREPITANT [INN]
APREPITANT [JAN]
Aprepitant(MK-0869)
C23H21F7N4O3
CHEMBL1471
APREPITANT [VANDF]
DTXSID3049047
D0GU4K
Aprepitant (MK-0869)
Aprepitant [USAN:INN:JAN]
APREPITANT [MART.]
ATALOFNDEOCMKK-OITMNORJSA-N
APREPITANT [USP-RS]
APREPITANT [WHO-DD]
MFCD08277635
Aprepitant (JAN/USP/INN)
Aprepitant Related Compound A
cc-310
MLS006011068
Aprepitant (JAN/USAN/INN)
APREPITANT [EMA EPAR]
L-754030
NSC-748825
SCHEMBL264924
SCHEMBL280611
CHEBI:499361
MK 869
Aprepitant - Bio-X trade mark
DTXCID801021794
GTPL3490
orb1307556
SCHEMBL7117513
APREPITANT [ORANGE BOOK]
CTK4D3687
MK 0869
A04AD12
AOB6779
APREPITANT [EP MONOGRAPH]
EX-A212
MK0869
APREPITANT [USP MONOGRAPH]
GLXC-05008
HMS2090N12
HMS3714E16
HMS3884G05
MK869
ONO 7436
Tox21_113595
ABP000600
BDBM50220136
EBC-11285
EBC-27288
HY-10052R
MFCD12912491
MK0517
NSC748825
s1189
ZINC27428713
AKOS015895498
AKOS015969344
Tox21_113595_1
ACN-037208
BCP9000312
C23-H21-F7-N4-O3
CCG-220747
CCG-264854
CID6918365
CS-0487
DB00673
FA17962
MK-0517
NSC 748825
RL02193
L 754030
L-754,030
NCGC00181785-01
NCGC00181785-03
NCGC00181785-11
NCGC00181785-12
NCGC00344566-01
AS-14638
BA164216
HY-10052
L982
SMR002530053
SY027654
Aprepitant (MK-0869, L-754030)?
A3135
Aprepitant,MK-0869, L-754030, Emend
CAS-170729-80-3
FT-0658107
MK-869, L-754030, Emend, Aprepitant
5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
J1.059.639D
A10083
A24972
C21555
D02968
EN300-761455
SBI-0654102.0001
W-5373
AB01274775-01
AB01274775_02
AB01275535-01
729A803
L754030
SR-05000001531
5-[2(R)-[1(R)-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY]-3(S)-(4-FLUOROPHENYL)MORPHOLIN-4-YLMETHYL]-3,4-DIHYDRO-2H-1,2,4-TRIAZOL-3-ONE
I06-1151
L754,030
SR-05000001531-1
BRD-K52827117-001-01-6
L 754,030
5-[[(2R,3S)-2-[(1R)-1-[3,5-BIS(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
Z2937147473
B2692-461949
3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one
3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
321125-94-4
3H-1,2,4-Triazol-3-one, 5-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-1,2-dihydro-
5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one
5-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-2,3-dihydro-1H-1,2,4-triazol-3-one
Aprepitant, United States Pharmacopeia (USP) Reference Standard
3-(((2R,3S)-3-(p-Fluorophenyl)-2-(((alphaR)-alpha-methyl-3,5-bis(trifluoromethyl)benzyl)oxy)morpholino)methyl)-Delta(2)-1,2,4-triazolin-5-one
3-(((2R,3S)-3-(p-Fluorophenyl)-2-(((alphaR)-alpha-methyl-3,5-bis(trifluoromethyl)benzyl)oxy)morpholino)methyl)-delta(sup 2)-1,2,4-triazolin-5-one
3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
3H-1,2,4-Triazol-3-one, 5-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,4-dihydro-
5-[(2R,3S)-2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3-(4-fluoro-phenyl)-morpholin-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one
5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
5-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
(2R)-3alpha-(4-Fluorophenyl)-4-[5(4H)-oxo-1H-1,2,4-triazole-3-ylmethyl]-2alpha-[[(R)-alpha-methyl-3,5-bis(trifluoromethyl)benzyl]oxy]morpholine
1148113-53-4
221350-96-5
3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholin-4-yl)methyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
3-(((2R,3S)-3-(P-FLUOROPHENYL)-2-(((.ALPHA.R)-.ALPHA.-METHYL-3,5-BIS(TRIFLUOROMETHYL)BENZYL)OXY)MORPHOLINO)METHYL)-.DELTA.(SUP 2)-1,2,4-TRIAZOLIN-5-ONE.
3-[((2R,5-bis(trifluoromethyl)benzyl]oxy}morpholino)methyl]-.delta.2-1,2,4-triazolin-5-one
3-[[(2R)-2alpha-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3alpha-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazole-5(4H)-one
3-[[(2R)-2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3alpha-(4-fluorophenyl)morpholino]methyl]-4,5-dihydro-1H-1,2,4-triazole-5-one
3-[[(2R)-2alpha-[[(R)-alpha-Methyl-3,5-di(trifluoromethyl)benzyl]oxy]-3alpha-(4-fluorophenyl)morpholino]methyl]-4,5-dihydro-1H-1,2,4-triazole-5-one
3-[[(2R,3S)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazole-5(4H)-one
3-[[(2R,3S)-2-[[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl]oxy]-3-(4-fluorophenyl)morpholine-4-yl]methyl]-1H-1,2,4-triazole-5(4H)-one
3-[[(2R,3S)-2-[[(alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzyl]oxy]-3-(4-fluorophenyl)morpholine-4-yl]methyl]-1H-1,2,4-triazole-5(4H)-one
3-[[(2R,3S)-3-(4-Fluorophenyl)-2-[[(R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]oxy]morpholino]methyl]-1H-1,2,4-triazole-5(4H)-one
3-[[2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3alpha-(4-fluorophenyl)morpholine-4-yl]methyl]-1H-1,2,4-triazole-5(4H)-one
3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)-1,4-oxazinan-4-ylmethyl]-4,5-dihydro-1H-1,2,4-triazol-5-one
3h-1,2,4-triazol-3-ona, 5-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluorometil)fenil]etoxi]-3-(4-fluorofenil)-4-morfolinil]metil]-1,2-dihidro-
3H-1,2,4-Triazol-3-one, 5-((2-(1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-1,2-dihydro-, (2R-(2alpha(R*),3alpha))-
3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-, rel-
3H-1,2,4-Triazol-3-one,5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-,rel-
3H-1,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
5-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-1,2-dihydro-3H-1,2,4-Triazol-3-one
5-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholin-4-yl)methyl)-1,2-dihydro-1,2,4-triazol-3-one
5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2H-1,2,4-triazol-3(4H)-one
5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol- 3-one
5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Aprepitant; Emend; L 754030; MK 0869; MK 869; ONO 7436; 3H-1,2,4-Triazol-3-one, 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-, [2R-[2alpha(R*),3alpha]]-
5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1,2-dihydro-3H-1,2,4-triazole-3-one
5-[[(2R,3S)-2-[(R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-3(2H)-one
5-[[2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3alpha-(4-fluorophenyl)morpholino]methyl]-2,4-dihydro-3H-1,2,4-triazole-3-one
5-[2-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3-(4-fluoro-phenyl)-morpholin-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one
5-{[(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1,2-dihydro-3H-1,2,4-triazol-3-one
677-636-6