Primary Record
ASTX029
- In stock
- 2,366 g
- Purity
- 98.8 %
- CAS
- 2095719-92-7
Compound Identifiers & Properties
- CAS
- 2095719-92-7
- PubChem CID
- 129053037
- SMILES
- C[C@H](C(=O)N[C@H](CO)C1=CC(=CC(=C1)F)OC)N2CC3=C(C2=O)C=C(C=C3)C4=NC(=NC=C4Cl)NC5CCOCC5
- Canonical SMILES
- COc1cc(F)cc([C@@H](CO)NC(=O)[C@@H](C)N2Cc3ccc(-c4nc(NC5CCOCC5)ncc4Cl)cc3C2=O)c1
Names & Synonyms
- ASTX029
- ERK1/2 inhibitor 2
- Beroterkib
- Beroterkib anhydrous
- ASTX-029
- 2095719-92-7
- beroterkib [INN]
- Astx 029
- 14FDK6ISC9
- RefChem:115372
- UNII-14FDK6ISC9
- C29H31ClFN5O5
- orb1298905
- CHEMBL4847260
- SCHEMBL18765557
- SCHEMBL29400079
- SCHEMBL29675949
- GTPL11727
- AT-35029
- BDBM418007
- GLXC-24264
- AT35029
- EX-A4375
- NSC836440
- US10457669, Example 685
- AKOS040759413
- ERK1/2 inhibitor 2(ASTX-029)?
- NSC-836440
- US10457669, Example 1083
- (alphaR)-6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-1,3-dihydro-alpha-methyl-1-oxo-2H-isoindole-2-acetamide
- compound 15 [PMID: 34387469]
- AC-36904
- TS-09810
- HY-126288
- CS-0101412
- G17546
- A939286
- (2R)-2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide
- (R)-2-(6-(5-Chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-1-oxoisoindolin-2-yl)-N-((S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)propanamide
- (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide
- (|AR)-6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-1,3-dihydro-|A-methyl-1-oxo-2H-isoindole-2-acetamide
- (2R)-2-(6-(5-Chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide
- (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1,3-dihydro-2H-1-oxoisoindol-2-yl)-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide
- (2R)-2-[6-[5-chloro-2-(tetrahydropyran-4-ylamino)pyrimidin-4-yl]-1-oxo-isoindolin-2-yl]-N-[(1S)-1-(3-fluoro-5-methoxy-phenyl)-2-hydroxy-ethyl]propanamide
- (2R)-2-{6-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-1-oxo-3H-isoindol-2-yl}-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide
- (aR)-6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-1,3-dihydro-a-methyl-1-oxo-2H-isoindole-2-acetamide
- (R)-2-(6-{5-Chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]pyrimidin-4-yl}-1-oxoisoindolin-2-yl)-N-[(S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propenamide
- 2H-Isoindole-2-acetamide, 6-(5-chloro-2-((tetrahydro-2H-pyran-4-yl)amino)-4-pyrimidinyl)-N-((1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)-1,3-dihydro-alpha-methyl-1-oxo-, (alphaR)-
- 2H-Isoindole-2-acetamide, 6-[5-chloro-2-[(tetrahydro-2H-pyran-4-yl)amino]-4-pyrimidinyl]-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]-1,3-dihydro-alpha-methyl-1-oxo-, (alphaR)-
- N/A
- RYW