Chemical Compound

Kyndrisa

CAS Registry Number 1251830-50-8
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Kyndrisa chemical structure
Primary Record

Kyndrisa

In stock
1,756 g
Purity
98.1 %
CAS
1251830-50-8

Compound Identifiers & Properties

CAS
1251830-50-8
PubChem CID
121494119
SMILES
CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COP(=S)(O)O[C@@H]3[C@H](O[C@H]([C@@H]3OC)N4C=CC(=NC4=O)N)COP(=S)(O)O[C@@H]5[C@H](O[C@H]([C@@H]5OC)N6C=CC(=O)NC6=O)COP(=S)(O)O[C@@H]7[C@H](O[C@H]([C@@H]7OC)N8C=CC(=O)NC8=O)COP(=S)(O)O[C@@H]9[C@H](O[C@H]([C@@H]9OC)N1C=CC(=O)NC1=O)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C(N=CN=C21)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=CC(=NC1=O)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C1N=C(NC2=O)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C1N=C(NC2=O)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=CC(=O)NC1=O)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C(N=CN=C21)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C1N=C(NC2=O)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C(N=CN=C21)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C(N=CN=C21)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C1N=C(NC2=O)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C1N=C(NC2=O)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C(N=CN=C21)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=NC2=C(N=CN=C21)N)COP(=O)(O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=CC(=NC1=O)N)COP(=S)(O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N1C=CC(=O)NC1=O)CO)S)O
Canonical SMILES
CO[C@@H]1[C@H](O)[C@@H](COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3ccc(=O)[nH]c3=O)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3ccc(=O)[nH]c3=O)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3ccc(=O)[nH]c3=O)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(=O)[nH]c(N)nc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(=O)[nH]c(N)nc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3ccc(=O)[nH]c3=O)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(=O)[nH]c(N)nc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(=O)[nH]c(N)nc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(=O)[nH]c(N)nc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(=O)(S)O[C@H]2[C@@H](OC)[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(O)(=S)O[C@H]2[C@@H](OC)[C@H](n3ccc(=O)[nH]c3=O)O[C@@H]2CO)O[C@H]1n1ccc(=O)[nH]c1=O

Names & Synonyms

  • Kyndrisa
  • DRISAPERSEN
  • Drisapersen [USAN:INN]
  • UNII-73D586DAMF
  • 73D586DAMF
  • H51AON23
  • GSK2402968A
  • GSK 2402968A
  • RNA, (P-thio)(Um-Cm-Am-Am-Gm-Gm-Am-Am-Gm-Am-Um-Gm-Gm-Cm-Am-Um-Um- Um-Cm-Um)
  • 1251830-50-8
  • All-P-ambo-2'-O-methyl-P-thiouridylyl-(3'->5')-2'-O-methyl-P-thiocytidylyl-(3'->5')-2'-O- methyl-P-thioadenylyl-(3'->5')-2'-O-methyl-P-thioadenylyl-(3'->5')-2'-O-methyl-P- thioguanylyl-(3'->5')-2'-O-methyl-P-thioguanylyl-(3'->5')-2'-O-methyl-P-thioadenylyl- (3'->5')-2'-O-methyl-P-thioadenylyl-(3'->5')-2'-O-methyl-P-thioguanylyl-(3'->5')-2'-O- methyl-P-thioadenylyl-(3'->5')-2'-O-methyl-P-thiouridylyl-(3'->5')-2'-O-methyl-P- thioguanylyl-(3'->5')-2'-O-methyl-P-thioguanylyl-(3'->5')-2'-O-methyl-P-thiocytidylyl- (3'->5')-2'-O-methyl-P-thioadenylyl-(3'->5')-2'-O-methyl-P-thiouridylyl-(3'->5')-2'-O- methyl-P-thiouridylyl-(3'->5')-2'-O-methyl-P-thiouridylyl-(3'->5')-2'-O-methyl-P- thiocytidylyl-(3'->5')-2'-O-methyluridine