Chemical Compound

Giredestrant

CAS Registry Number 1953133-47-5
Giredestrant chemical structure
Primary Record

Giredestrant

In stock
872 g
Purity
98.8 %
CAS
1953133-47-5

Compound Identifiers & Properties

CAS
1953133-47-5
PubChem CID
121410806
SMILES
C[C@@H]1CC2=C([C@H](N1CC(CO)(F)F)C3=C(C=C(C=C3F)NC4CN(C4)CCCF)F)NC5=CC=CC=C25
Canonical SMILES
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CN(CCCF)C3)cc2F)N1CC(F)(F)CO

Names & Synonyms

  • Giredestrant
  • Giredestrant?
  • GDC-9545
  • Giredestrant [INN]
  • Giredestrant [USAN]
  • 1953133-47-5
  • RefChem:143240
  • 28P3DU6DB3
  • Giredestrant (USAN/INN)
  • Giredestrant [USAN:INN]
  • UNII-28P3DU6DB3
  • RO7197597
  • GIREDESTRANT [WHO-DD]
  • SERD GDC-9545
  • GDC9545
  • GQCXHIKRWBIQMD-AKJBCIBTSA-N
  • orb1309629
  • CHEMBL4650316
  • RO-7197597
  • SCHEMBL17839430
  • SCHEMBL29356127
  • GTPL12715
  • RG6171
  • DTXSID101385117
  • EX-A3541
  • GDC 9545
  • BDBM50572808
  • GDC-49545
  • NSC827275
  • WHO 11226
  • AKOS040733254
  • AT22918
  • NSC-827275
  • RG-6171
  • compound 35 [PMID: 34251202]
  • AC-37111
  • DA-63770
  • MS-29682
  • HY-109176
  • CS-0116370
  • D11961
  • Selective Estrogen Receptor Degrader GDC-9545
  • 3-[(1R,3R)-1-[2,6-difluoro-4-[[1-(3-fluoropropyl)azetidin-3-yl]amino]phenyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-2,2-difluoropropan-1-ol
  • A1016112
  • Selective Estrogen Receptor Downregulator GDC-9545
  • 3-((1R,3R)-1-(2,6-Difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido(3,4-b)indol-2-yl)-2,2-difluoropropan-1-ol
  • 3-((1R,3R)-1-(2,6-Difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol
  • (1R,3R)-1-(2,6-Difluoro-4-((1-(3-fluoropropyl)-3-azetidinyl)amino)phenyl)-beta,beta-difluoro-1,3,4,9-tetrahydro-3-methyl-2H-pyrido(3,4-b)indole-2-propanol
  • 2H-Pyrido(3,4-b)indole-2-propanol, 1-(2,6-difluoro-4-((1-(3-fluoropropyl)-3-azetidinyl)amino)phenyl)-beta,beta-difluoro-1,3,4,9-tetrahydro-3-methyl-, (1R,3R)-
  • 3-[(1R,3R)-1-(2,6-difluoro-4-{[1-(3-fluoropropyl)azetidin-3-yl]amino}phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl]-2,2-difluoropropan-1-ol
  • (1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)-3-AZETIDINYL)AMINO)PHENYL)-.BETA.,.BETA.-DIFLUORO-1,3,4,9-TETRAHYDRO-3-METHYL-2H-PYRIDO(3,4-B)INDOLE-2-PROPANOL
  • (1R,3R)-1-[2,6-Difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]amino]phenyl]-|A,|A-difluoro-1,3,4,9-tetrahydro-3-methyl-2H-pyrido[3,4-b]indole-2-propanol
  • (1R,3R)-1-[2,6-Difluoro-4-[[1-(3-fluoropropyl)-3-azetidinyl]amino]phenyl]-beta,beta-difluoro-1,3,4,9-tetrahydro-3-methyl-2H-pyrido[3,4-b]indole-2-propanol
  • 2H-PYRIDO(3,4-B)INDOLE-2-PROPANOL, 1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)-3-AZETIDINYL)AMINO)PHENYL)-.BETA.,.BETA.-DIFLUORO-1,3,4,9-TETRAHYDRO-3-METHYL-, (1R,3R)-
  • 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydropyrido(3,4-b)indol-2-yl)-2,2-difluoropropan-1-ol
  • 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)-2,2-difluoropropan-1-ol
  • 3-[(1R,3R)-1-(2,6-difluoro-4-{[1-(3-fluoropropyl)azetidin-3-yl]amino}phenyl)-3-methyl-1H,3H,4H,9H-pyrido[3,4-b]indol-2-yl]-2,2-difluoropropan-1-ol
  • 3-[(1R,3R)-1-[2,6-difluoro-4-[[1-(3-fluoropropyl)azetidin-3-yl]amino]phenyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-2,2-difluoro-propan-1-ol
  • ZNM