Chemical Compound

Semaglutide

CAS Registry Number 99291-20-0
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Semaglutide chemical structure
Primary Record

Semaglutide

In stock
2,795 g
Purity
98.5 %
CAS
99291-20-0

Compound Identifiers & Properties

CAS
99291-20-0
PubChem CID
10440910
SMILES
C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)N
Canonical SMILES
CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)C(C)C)C(C)C)C(C)C)C(=O)O

Names & Synonyms

  • Semaglutide
  • V-9-M Cholecystokinin nonapeptide
  • Cholecystokinin Precursor (24-32) (rat)
  • Prepro CCK Fragment V-9-M
  • orb1741473
  • 99291-20-0
  • HY-P2636
  • CID10440910
  • TS-10619
  • CS-0137121
  • H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OH
  • G77861
  • Cholecystokinin Precursor (24-32) (rat) H-Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met-OH
  • (3S,6S,9S,12S,15S)-1-((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)-15-((S)-2-(((S)-1-carboxy-3-(methylthio)propyl)carbamoyl)pyrrolidine-1-carbonyl)-6-(2-carboxyethyl)-3,12-diisopropyl-9-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazaheptadecan-17-oic acid
  • (S)-4-((S)-2-((S)-1-(L-valyl)pyrrolidine-2-carboxamido)-3-methylbutanamido)-5-(((S)-1-(((S)-1-(((S)-3-carboxy-1-((S)-2-(((S)-1-carboxy-3-(methylthio)propyl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
Custom Synthesis

Semaglutide Custom Synthesis Services

Explore our custom synthesis capabilities for Semaglutide-related peptides, building blocks, intermediates, impurities and analytical reference materials. Custom requirements and specifications can be discussed with our team.

Peptide Sequence Modification

Custom sequence variants and terminal modifications for Semaglutide research.

  • Amino Acid Substitution
  • Aib Substitution Studies
  • D-Amino Acid Incorporation
  • Sequence Truncation
  • Sequence Extension
  • N-Terminal Modification
  • C-Terminal Modification

Semaglutide Analogs

Custom synthesis of structurally modified Semaglutide peptide analogs.

  • Sequence Variants
  • GLP-1 Peptide Analogs
  • Modified Peptide Derivatives

Lipidated Derivatives

Custom studies of Lys26-linked fatty diacid conjugates and related lipidated peptide derivatives.

  • C18 Fatty Diacid Derivatives
  • Fatty Acid Chain Variants
  • Lys26 Lipidation Variants
  • Lipidated Peptide Analogs

Linkers & Chemical Intermediates

Custom synthesis of hydrophilic spacers and lipid-linker building blocks.

  • AEEA Linkers
  • Hydrophilic Linkers
  • γ-Glutamyl Linkers
  • Fatty Diacid-Linker Intermediates

Amino Acid Building Blocks

Custom synthesis of modified and protected amino acid building blocks relevant to Semaglutide.

  • Aib Derivatives
  • Fmoc-Protected Amino Acids
  • Boc-Protected Amino Acids
  • D-Amino Acids
  • Side-Chain Protected Amino Acids
  • Isotope-Labeled Amino Acids

Peptide Fragments

Custom synthesis of Semaglutide-related peptide fragments and protected intermediates.

  • N-Terminal Peptide Fragments
  • C-Terminal Peptide Fragments
  • Internal Peptide Fragments
  • Protected Peptide Fragments
  • Lipidated Peptide Fragments

Impurities & Degradation Products

Custom synthesis of process-related and degradation-related Semaglutide impurities.

  • Deletion Peptide Impurities
  • Insertion Peptide Impurities
  • Sequence-Related Impurities
  • Epimerization Impurities
  • Oxidation Products
  • Deamidation Products
  • Lipidation-Related Impurities

Isotope-Labeled Semaglutide

Custom synthesis of stable isotope-labeled Semaglutide and peptide fragments.

  • 13C-Labeled Semaglutide
  • 15N-Labeled Semaglutide
  • 13C/15N-Labeled Peptides
  • Deuterium-Labeled Peptides
  • Isotope-Labeled Peptide Fragments

Reference Standards

Custom synthesis of analytical reference materials for Semaglutide testing.

  • Semaglutide Reference Standards
  • Working Standards
  • Impurity Reference Standards
  • System Suitability Standards
  • Analytical Peptide Standards