Chemical Compound

5-(((2R,3R,4S)-3-(6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl)-5-oxatricyclo(4.4.0.0^(2,4))deca-1(6),7,9-trien-9-yl)oxy)-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one

CAS Registry Number 1446090-79-4
返回搜索 申请报价
5-(((2R,3R,4S)-3-(6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl)-5-oxatricyclo(4.4.0.0^(2,4))deca-1(6),7,9-trien-9-yl)oxy)-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one 结构式
Primary record

5-(((2R,3R,4S)-3-(6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl)-5-oxatricyclo(4.4.0.0^(2,4))deca-1(6),7,9-trien-9-yl)oxy)-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one

库存
1,688 克
纯度
98.5 %
CAS
1446090-79-4

化合物标识与属性

CAS
1446090-79-4
PubChem CID
89670174
SMILES
C1CC(=O)NC2=NC=CC(=C21)OC3=CC4=C(C=C3)O[C@H]5[C@@H]4[C@@H]5C6=NC7=C(N6)C=C(C=C7)C(F)(F)F
Canonical SMILES
O=C1CCc2c(Oc3ccc4c(c3)[C@@H]3[C@H](O4)[C@H]3c3nc4ccc(C(F)(F)F)cc4[nH]3)ccnc2N1

名称与同义词

  • lifirafenib
  • Beigene-283
  • BGB-283
  • lifirafenibum
  • Lifirafenib [USAN]
  • compound 2.2b
  • 1446090-79-4
  • Begeine-283
  • Bgb 283
  • BGB283
  • 1446090-77-2
  • RefChem:924746
  • 8762XZS5ZF
  • LIFIRAFENIB [INN]
  • UNII-8762XZS5ZF
  • Lifirafenib (USAN/INN)
  • BGB-283;Beigene-283
  • LIFIRAFENIB [WHO-DD]
  • GTPL8958
  • orb1146515
  • orb1905876
  • CHEMBL4209157
  • SCHEMBL15085288
  • SCHEMBL29358338
  • SCHEMBL29464034
  • SCHEMBL29749194
  • C25H17F3N4O3
  • NGFFVZQXSRKHBM-FKBYEOEOSA-N
  • BDBM372968
  • GLXC-15416
  • EX-A1473
  • US9895376, Compound 2.2b
  • WHC09077
  • WHC09079
  • Lifirafenib;BGB-283;Beigene-283
  • BDBM50453816
  • MFCD30489379
  • WHO 10554
  • ZINC68764621
  • 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
  • AKOS040745015
  • CS-6308
  • DB14773
  • AC-35880
  • AC-36373
  • DA-71454
  • HY-18957
  • MS-28874
  • D11410
  • G16023
  • A900647
  • A999887
  • 5-(((1R,1aS,6bR)-1-(6-(Trifluoromethyl)-1H-benzimidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa(b)benzofuran-5-yl)oxy)-3,4-dihydro-1H-1,8-naphthyridin-2-one
  • Q27075193
  • 5-[[(1R,1aS,6bR)-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
  • B0084-475450
  • 1,8-Naphthyridin-2(1H)-one, 5-(((1R,1aS,6bR)-1a,6b-dihydro-1-(6-(trifluoromethyl)-1H-benzimidazol-2-yl)-1H-cyclopropa(b)benzofuran-5-yl)oxy)-3,4-dihydro-
  • 1,8-Naphthyridin-2(1H)-one, 5-[[(1R,1aS,6bR)-1a,6b-dihydro-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1H-cyclopropa[b]benzofuran-5-yl]oxy]-3,4-dihydro-
  • 5-({(1r,1as,6br)-1-[5-(Trifluoromethyl)-1h-Benzimidazol-2-Yl]-1a,6b-Dihydro-1h-Cyclopropa[b][1]benzofuran-5-Yl}oxy)-3,4-Dihydro-1,8-Naphthyridin-2(1h)-One
  • 3K3
  • 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzimidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa(b)(1)benzofuran-5-yl)oxy)-3,4-dihydro-1H-1,8-naphthyridin-2-one
  • 5-(((2R,3R,4S)-3-(6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl)-5-oxatricyclo(4.4.0.0^(2,4))deca-1(6),7,9-trien-9-yl)oxy)-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one
  • 5-[[(1R,1aS,6bR)-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
  • 5-{[(2R,3R,4S)-3-[5-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]-5-oxatricyclo[4.4.0.0(2),?]deca-1(10),6,8-trien-9-yl]oxy}-3,4-dihydro-1H-1,8-naphthyridin-2-one
  • 5-{{(1r,1as,6br)-1-[5-(trifluoromethyl)-1h-benzimidazol-2-yl]-1a,6b-dihydro-1h-cyclopropa[b][1]benzofuran-5-yl}oxy}-3,4-dihydro-1,8-naphthyridin-2(1h)-one
  • Rel-5-(((1r,1as,6br)-1-(5-(trifluoromethyl)-1h-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1h-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1h)-one
  • rel-5-[[(1S,1aS,6bR)-1a,6b-dihydro-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1H-cyclopropa[b]benzofuran-5-yl]oxy]-3,4-dihydro1,8-Naphthyridin-2(1H)-one