Chemical Compound

1,2,4-Triazolo[4,3-a]pyrazine, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)- (9CI); (2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine; 3(R)-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; Sitagliptin, 1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)-

CAS Registry Number 486460-32-6
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1,2,4-Triazolo[4,3-a]pyrazine, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)- (9CI); (2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine; 3(R)-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; Sitagliptin, 1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)- 结构式
Primary record

1,2,4-Triazolo[4,3-a]pyrazine, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)- (9CI); (2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine; 3(R)-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; Sitagliptin, 1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)-

库存
5,714 克
纯度
98.8 %
CAS
486460-32-6

化合物标识与属性

CAS
486460-32-6
PubChem CID
4369359
SMILES
C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N
Canonical SMILES
N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F

名称与同义词

  • Sitagliptin
  • Januvia
  • 486460-32-6
  • Xelevia
  • Zituvio
  • sitagliptina
  • sitagliptine
  • Sitagliptan
  • sitagliptinum
  • Janumet
  • Sitagliptin phosphate
  • Tesavel
  • mine
  • ristaben
  • Sitagliptin Base
  • Stotigliptin
  • rac-Sitagliptin
  • Sitagliptin/
  • Sitagliptin [INN]
  • Januvia (TN)
  • Sitagliptin (13)
  • SitagliptinMK0431
  • Januvia (merck & Co.)
  • MK-0431
  • QFP0P1DV7Z
  • LEZ763
  • Sitagliptin/atovastatin
  • UNII-QFP0P1DV7Z
  • RefChem:6227
  • Tube110
  • Sitagliptin Hydrochloride
  • Sitagliptin; MK0431
  • (-)-(R)-Sitagliptin
  • AC1N9ZYR
  • Sitagliptin (Prop.INN)
  • Sitagliptin [INN:BAN]
  • SITAGLIPTIN [MI]
  • Sitagliptin (USAN/INN)
  • SITAGLIPTIN [HSDB]
  • SITAGLIPTIN [USAN]
  • C16H15F6N5O
  • D0P0HH
  • D0U2JP
  • SITAGLIPTIN [VANDF]
  • LEZ-763
  • CHEMBL1422
  • Sitagliptin phosphate hydrate
  • MFCD09838015
  • SCHEMBL17783
  • BSPBio_002262
  • SITAGLIPTIN [WHO-DD]
  • Sitagliptin phosphate monohydrate
  • Triazolopiperazine Analogue 1
  • CHEBI:40237
  • HSDB 7516
  • MLS006011959
  • sitagliptin phosphate anhydrous
  • DTXSID70197572
  • LEZ 763
  • MFFMDFFZMYYVKS-SECBINFHSA-N
  • SITAGLIPTIN [EMA EPAR]
  • Sitagliptin [USAN:INN:BAN]
  • CHEMBL393336
  • GTPL6286
  • orb1310801
  • Sitagliptin (Metformin,MK-0431)
  • SCHEMBL29365085
  • BDBM11162
  • ERK5-2I04
  • AMY6930
  • DTXCID30120063
  • 1x70
  • (R)-3-AMINO-1-(3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL)-4-(2,4,5-TRIFLUOROPHENYL)BUTAN-1-ONE
  • GLXC-15213
  • HMS2093F20
  • ZITUVIMET COMPONENT SITAGLIPTIN
  • ACT02665
  • AMX10120
  • EX-A2816
  • MK 0431
  • MSK11067
  • sitagliptin monophosphate monohydrate
  • WHO 8692
  • ZINC1489478
  • ABP000233
  • AN-404
  • BBF-05866
  • EBC-13573
  • NSC813215
  • AKOS015888724
  • ACN-037559
  • CB10244
  • CCG-268731
  • CID4369359
  • CS-2914
  • CS-O-31560
  • DB01261
  • FA31666
  • NSC-813215
  • RL03803
  • NCGC00178734-03
  • NCGC00178734-06
  • NCGC00178734-13
  • (3R)-3-AMINO-1-[3-(TRIFLUOROMETHYL)-5H,6H,7H,8H-[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7-YL]-4-(2,4,5-TRIFLUOROPHENYL)BUTAN-1-ONE
  • AJ-26333
  • AS-19118
  • HY-13749
  • SC-19743
  • SMR002546724
  • EC 690-730-1
  • SBI-0206871.P001
  • Sitagliptin 100 microg/mL in Acetonitrile
  • AB0006583
  • AB1004599
  • LS-187389
  • 2201B
  • A4036
  • C16-H15-F6-N5-O.H3-O4-P
  • FT-0650740
  • FT-0674600
  • FT-0693933
  • NS00000425
  • S5079
  • X4663
  • (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
  • J2.231.708C
  • A14377
  • A25516
  • D08516
  • EN300-119510
  • Q-1665
  • AB01563393_01
  • AR-270/43507782
  • F358083
  • Q419832
  • SR-05000001748
  • (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
  • (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
  • 790712-60-6
  • SR-05000001748-1
  • BRD-K19416115-001-01-2
  • BRD-K19416115-001-03-8
  • BRD-K19416115-001-05-3
  • BRD-K19416115-366-02-7
  • 1,2,4-Triazolo[4,3-a]pyrazine,7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-
  • Z1521553713
  • (3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
  • (2R)-4-OXO-4-(3-(TRIFLUOROMETHYL)-5,6-DIHYDRO(1,2,4)TRIAZOLO(4,3-A)PYRAZIN-7(8H)-YL)-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
  • 1,2,4-Triazolo(4,3-a)pyrazine, 7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8-tetrahydor-3-(trifluoromethyl)-
  • 654671-77-9
  • 7-((3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)buyl)-5,6,7,8-tetrahydro-3-trifluoromethyl)-1,4-triazolo(4,3-a)
  • 7-[(3r)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
  • (1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorobenzyl)propylamine
  • (2R)-4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine phosphate salt
  • (2r)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a] pyrazin-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine
  • (2r)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8h)-yl]-1-(2,4,5-trifluorophenyl)butan-2-a
  • (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE
  • (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-alpha]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine
  • (3R)-1-[3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-3-amino-4-(2,4,5-trifluorophenyl)-1-butanone
  • (3R)-1-[3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-3-amino-4-(2,4,5-trifluorophenyl)butan-1-one
  • (3R)-3-AMINO-1-(3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-1,2,4-TRIAZOLO(4,3-A)PYRAZIN-7-YL)-4-(2,4,5-TRIFLUOROPHENYL)BUTAN-1-ONE
  • (3R)-3-amino-1-(3-(trifluoromethyl)-5H,6H,7H,8H-(1,2,4)triazolo(4,3-a)pyrazin-7-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  • (3R)-3-amino-1-(3-(trifluoromethyl)-6,8-dihydro-5H-(1,2,4)triazolo(4,3-a)pyrazin-7-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  • (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
  • (3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[3,4-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride
  • (3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  • (R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine
  • (S)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  • 1,2,4-TRIAZOLO(4,3-A)PYRAZINE-7(8H)-PROPANAMINE, 5,6-DIHYDRO-.GAMMA.-OXO-3-(TRIFLUOROMETHYL)-.ALPHA.-((2,4,5-TRIFLUOROPHENYL)METHYL)-, (.ALPHA.R)-
  • 1,2,4-Triazolo[4,3-a]pyrazine, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)- (9CI); (2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine; 3(R)-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; Sitagliptin, 1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)-
  • 1169707-31-6
  • 3-oxo-1-(2,4,5-trifluorobenzyl)-3-(3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)propylamine
  • 4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine
  • 690-730-1
  • 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)buyl]-5,6,7,8-tetrahydro-3-trifluoromethyl)-1,4-triazolo[4,3-a]
  • 823817-56-7