Primary record
N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]pyrazin-2- yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)benzamide (317)
- 库存
- 9,677 克
- 纯度
- 99.1 %
- CAS
- 1073154-85-4
化合物标识与属性
- CAS
- 1073154-85-4
- PubChem CID
- 25117126
- SMILES
- CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F
- Canonical SMILES
- CNC(=O)c1ccc(Nc2ncc(C(F)(F)F)c(NCc3nccnc3N(C)S(C)(=O)=O)n2)cc1
名称与同义词
- Defactinib
- 1073154-85-4
- defactinibum
- Defacitinib
- VS-6063
- PF-04554878
- Defactinib [USAN]
- Defactinib [USAN:INN]
- Defactinib hydrochloride
- DEFACTINIB [INN]
- Defactinib (USAN/INN)
- RefChem:919757
- 53O87HA2QU
- UNII-53O87HA2QU
- C20H21F3N8O3S
- D0V6EV
- D0Y1UO
- DEFACTINIB [WHO-DD]
- MFCD25977806
- GTPL7910
- orb1183414
- orb1306800
- SCHEMBL1627234
- CHEMBL3137331
- FAK inhibitors (cancer), Pfizer
- Defactinib (PF-04554878)
- FWLMVFUGMHIOAA-UHFFFAOYSA-N
- 1345713-71-4
- BDBM418817
- DTXSID901025937
- GLXC-90041
- HMS3740O13
- AMY42170
- AOB87723
- BCP11299
- Defactinib (VS-6063, PF-04554878)
- EX-A1037
- EX-A1049
- VS 6063
- 2-(3-Chloro-phenylsulfanyl)-ethanol
- 2361AH
- NSC778364
- NSC781450
- NSC782549
- NSC800089
- s7654
- VS6063
- US10450297, Example 317
- US10450297, Example 318
- AKOS026750300
- N-methyl-4-((4-(((3-(N-methylmethylsulfonamido)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide
- ZINC103297739
- CCG-269780
- CS-3410
- DB12282
- NSC-778364
- NSC-781450
- NSC-782549
- NSC-800089
- SB17060
- NCGC00386425-06
- NCGC00386425-11
- AC-35820
- AK546976
- AS-17045
- BC600623
- DA-34914
- DA-45890
- FD103987
- HY-12289
- PF 04554878
- N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
- PF-941222
- B4800
- FT-0706351
- FT-0721609
- NS00073320
- PF-4554878
- J3.502.756D
- A11929
- D10618
- Defactinib (VS-6063, PF-04554878)?
- A857460
- A887883
- Avmapki Fakzynja (avutometinib + defactinib co-pack)
- BRD-K43578482-001-01-4
- BRD-K43578482-001-02-2
- Q27077009
- Benzamide, N-methyl-4-((4-(((3-(methyl(methylsulfonyl)amino)-2-pyrazinyl)methyl)amino)-5-(trifluoromethyl)-2-pyrimidinyl)amino)-
- B0084-462762
- N-methyl-4-((4-(((3-methyl(methylsulfonyl)aminopyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide
- ~{N}-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
- N-Methyl-4-((4-(((3-(methyl(methylsulfonyl)amino)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide
- 1073160-26-5
- 4-[[4-[[3-[Methyl(methylsulfonyl)amino]pyrazin-2-ylmethyl]amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-N-methylbenzamide
- 7KD
- N-methyl-4-((4-(((3-(N-methylmethanesulfonamido)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide
- N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]pyrazin-2- yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)benzamide (317)
- N-methyl-4-(4-((3-(N-methylmethylsulfonamido)pyrazin-2-yl)methylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)benzamide
- N-Methyl-4-[[4-[[[3-[methyl(methylsulfonyl)amino]-2-pyrazinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]benzamide
- N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-trifluoromethylpyrimidin-2-yl]amino]benzamide
- N-METHYL-4-{[4-({[3-(N-METHYLMETHANESULFONAMIDO)PYRAZIN-2-YL]METHYL}AMINO)-5-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]AMINO}BENZAMIDE