Primary record
N-[3-Fluoro-4-[[4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl]methyl]-2-pyridinyl]-N inverted exclamation marka-methylsulfamide
- 库存
- 9,433 克
- 纯度
- 98.1 %
- CAS
- 946128-88-7
化合物标识与属性
- CAS
- 946128-88-7
- PubChem CID
- 16719221
- SMILES
- CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F
- Canonical SMILES
- CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F
名称与同义词
- avutometinib
- 946128-88-7
- 3wig
- RO5126766
- CH5126766
- RO-5126766
- Ro 5126766
- CKI-27
- Ro 5126766 - Bio-X
- RO-5126766 free base
- Avutometinib [WHO-DD]
- RefChem:115811
- Avutometinib (USAN/INN)
- AVUTOMETINIB [INN]
- VS-6766
- CHEBI:78825
- AVUTOMETINIB [USAN]
- CH-5126766
- RG-7304
- CHEMBL3264002
- SCHEMBL960093
- C21H18FN5O5S
- orb1300300
- Raf/MEK Inhibitor VS-6766
- D0D4252V97
- SCHEMBL29358292
- SCHEMBL29360048
- SCHEMBL29515377
- UNII-D0D4252V97
- GTPL11867
- RG7304
- DTXSID601356850
- GLXC-07174
- BCP21067
- EX-A2151
- RO5126766(CH5126766)
- BDBM50010462
- MFCD27987901
- NSC758248
- NSC800871
- R-7304
- s7170
- VS6766
- ZINC68247388
- AKOS030527032
- ACN-038040
- CCG-269457
- compound 1 [PMID: 24900832]
- CS-5254
- DB15254
- NSC-758248
- NSC-800871
- RG 7304
- SB16628
- VS 6766
- RO5126766 (CH5126766)
- AC-35949
- BC600429
- CID:16719221
- DA-40233
- FR103619
- HY-18652
- MS-28717
- SID:163563846
- B5820
- CH 5126766
- FT-0737411
- 3-[[2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl]-4-methyl-7-[(pyrimidin-2-yl)oxy]-2H-1-benzopyran-2-one
- J3.320.809J
- A14019
- D12515
- A916428
- C577924
- RO5126766; CH5126766
- Avmapki Fakzynja (avutometinib + defactinib co-pack)
- BRD-K82804538-001-01-0
- BRD-K82804538-001-02-8
- Q27147976
- 3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-4-methyl-7-pyrimidin-2-yloxychromen-2-one
- N-(3-Fluoro-4-{[4-Methyl-2-Oxo-7-(Pyrimidin-2-Yloxy)-2h-Chromen-3-Yl]methyl}pyridin-2-Yl)-N'-Methylsulfuric Diamide
- N-[3-fluoro-4-({4-methyl-2-oxo-7-[(pyrimidin-2-yl)oxy]-2H-1-benzopyran-3-yl}methyl)pyridin-2-yl]-N'-methylsulfuric diamide
- Sulfamide, N-(3-fluoro-4-((4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl)methyl)-2-pyridinyl)-N'-methyl-
- Sulfamide, N-[3-fluoro-4-[[4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl]methyl]-2-pyridinyl]-N'-methyl-
- RO 5126766; RO5126766; CH5126766; CH5126766; CH 5126766
- 2-[[(Methylamino)sulfonyl]amino]-4-[[4-methyl-7-(pyrimidine-2-yloxy)-2-oxo-2H-1-benzopyran-3-yl]methyl]-3-fluoropyridine
- 213406-50-9
- 3-({3-fluoro-2-[(methylsulfamoyl)amino]pyridin-4-yl}methyl)-4-methyl-7-(pyrimidin-2-yloxy)-2H-chromen-2-one
- 3-({3-FLUORO-2-[(METHYLSULFAMOYL)AMINO]PYRIDIN-4-YL}METHYL)-4-METHYL-7-(PYRIMIDIN-2-YLOXY)CHROMEN-2-ONE
- 3-[[3-fluoro-2-(methylsulfamoylamino)-4-pyridyl]methyl]-4-methyl-7-pyrimidin-2-yloxy-chromen-2-one
- 3-[3-Fluoro-2-[(methylsulfamoyl)amino]-4-pyridylmethyl]-7-(2-pyrimidinyloxy)-4-methyl-2H-1-benzopyran-2-one
- 3-{2-(methylaminosulfonyl)amino-3-fluoropyridin-4-ylmethyl}-4-methyl-7-(pyrimidin-2-yloxy)-2-oxo-2h-1-benzopyran
- CHU
- N-(3-fluoro-4-((4-methyl-2-oxo-7-((pyrimidin-2-yl)oxy)-2H-1-benzopyran-3-yl)methyl)pyridin-2-yl)-N'-methylsulfuric diamide
- N-[3-Fluoro-4-[[4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl]methyl]-2-pyridinyl]-N inverted exclamation marka-methylsulfamide
- N-[3-Fluoro-4-[[4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl]methyl]-2-pyridinyl]-N'-methylsulfamide