Chemical Compound

2-[4-[1-[17-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-1-piperazinyl]-16-oxo-3,6,9,12-tetraoxa-15-azaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]phenyl]-2H-indazole-7-carboxamide

CAS Registry Number 2369022-68-2
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2-[4-[1-[17-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-1-piperazinyl]-16-oxo-3,6,9,12-tetraoxa-15-azaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]phenyl]-2H-indazole-7-carboxamide 结构式
Primary record

2-[4-[1-[17-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-1-piperazinyl]-16-oxo-3,6,9,12-tetraoxa-15-azaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]phenyl]-2H-indazole-7-carboxamide

库存
6,552 克
纯度
99.8 %
CAS
2369022-68-2

化合物标识与属性

CAS
2369022-68-2
PubChem CID
138454769
SMILES
CC(C)OC1=C(C=CC(=C1)OC)C2=N[C@@H]([C@@H](N2C(=O)N3CCN(C(=O)C3)CC(=O)NCCOCCOCCOCCOCCN4C=C(N=N4)C5=CC=C(C=C5)N6C=C7C=CC=C(C7=N6)C(=O)N)C8=CC=C(C=C8)Cl)C9=CC=C(C=C9)Cl
Canonical SMILES
COc1ccc(C2=N[C@H](c3ccc(Cl)cc3)[C@H](c3ccc(Cl)cc3)N2C(=O)N2CCN(CC(=O)NCCOCCOCCOCCOCCn3cc(-c4ccc(-n5cc6cccc(C(N)=O)c6n5)cc4)nn3)C(=O)C2)c(OC(C)C)c1

名称与同义词

  • PROTAC PARP1 degrader
  • PARP1 PROTAC compound 3
  • rel-PROTAC PARP1 degrader
  • PARP1-targeting PROTAC 3
  • orb1989660
  • CHEMBL5284804
  • SCHEMBL29881189
  • YQF1936
  • GLXC-26105
  • EX-A9077
  • 2369022-68-2
  • AKOS037653399
  • HY-114324
  • CS-0082106
  • G76798
  • A1021861
  • 2-(4-(1-(1-(4-((4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)-2-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-17-yl)-1H-1,2,3-triazol-4-yl)phenyl)-2H-indazole-7-carboxamide
  • 2-[4-[1-[2-[2-[2-[2-[2-[[2-[4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-2-oxopiperazin-1-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]phenyl]indazole-7-carboxamide
  • 2-(4-(1-(1-(4-((4R,5S)-4,5-bBs(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)-2-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-17-yl)-1H-1,2,3-triazol-4-yl)phenyl)-2H-indazole-7-carboxamide
  • 2-[4-[1-[17-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-oxo-1-piperazinyl]-16-oxo-3,6,9,12-tetraoxa-15-azaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]phenyl]-2H-indazole-7-carboxamide