Chemical Compound
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-; 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)- (9CI); BIBF 1120; Nintedanib; Ofev; Vargatef
CAS Registry Number
656247-17-5
Primary record
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-; 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)- (9CI); BIBF 1120; Nintedanib; Ofev; Vargatef
- 库存
- 7,937 克
- 纯度
- 98.8 %
- CAS
- 656247-17-5
化合物标识与属性
- CAS
- 656247-17-5
- PubChem CID
- 135423438
- SMILES
- CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
- Canonical SMILES
- COC(=O)c1ccc2c(C(=Nc3ccc(N(C)C(=O)CN4CCN(C)CC4)cc3)c3ccccc3)c(O)[nH]c2c1
名称与同义词
- Nintedanib
- Vargatef
- Intedanib
- BIBF-1120
- 656247-17-5
- BIBF 1120
- Lenvatinib
- BIBF1120
- OFEV
- nibtedanib
- null
- Nintedanib (BIBF 1120)
- Vargatef Base
- Intedanib-d3
- Nintedanib [INN]
- Nintedanib D3
- Nintedanib E-isomer
- Nintedanib esylate
- Nintedanib [USAN]
- (E)-Nintedanib
- 928326-83-4
- Vargatef (TN)
- Nintedanib (Standard)
- Nintedanib [USAN:INN]
- Nintedanib, Free Base
- Ofev (TN)
- BIBF1120,Vargatef
- Tube722
- Nintedanib (free base)
- 2-(Hexadecyloxy)ethanol
- INTEDANIB [MI]
- Bibf1120 - Vargatef
- Nintedanib ethanesulfonate
- Nintedanib (USAN/INN)
- UNII-G6HRD2P839
- BIBF1120 (Vargatef)
- NINTEDANIB [VANDF]
- Vargatef, BIBF 1120
- cc-88
- D09HNV
- D0J1OJ
- G6HRD2P839
- NINTEDANIB [WHO-DD]
- MFCD11974012
- Nintedanib (BIBF-1120)
- MLS006010165
- SCHEMBL431006
- SCHEMBL431007
- Nintedanib (BIBF 1120)?
- US10669235, Nintedanib
- C31H33N5O4
- CHEMBL502835
- GTPL5936
- Nintedanib - Bio-X trade mark
- orb1183654
- orb1307463
- QCR-43
- SCHEMBL1535871
- OFEV COMPONENT NINTEDANIB
- CHEMBL2136735
- SCHEMBL25226025
- SCHEMBL29352914
- CHEBI:85164
- CHEBI:91413
- HSDB 8339
- AMY9163
- AOB5742
- CID 9809715
- DTXSID20918936
- EX-A341
- SYN1091
- XZXHXSATPCNXJR-ZIADKAODSA-N
- 1160294-26-7
- BDBM445209
- BDBM734449
- DTXSID201025948
- GLXC-06034
- HMS3244B06
- HMS3244B10
- HMS3244B14
- HMS3295K01
- HMS3654A05
- HMS5079G03
- BCP01744
- BCP09316
- EBD48532
- EX-A2818
- KS-000004AN
- KWB29426
- ZPC58784
- ABP000857
- ARD179559
- BDBM50026612
- EBC-11367
- HY-50904R
- NSC756659
- NSC757442
- NSC800805
- RS0107
- s1010
- ZINC22449469
- AKOS005145820
- AKOS025401745
- AKOS026750205
- BIBF 1120|||Intedanib|||Vargatef
- BIBF1120,BIBF-1120,Vargatef/
- ZINC100014909
- ACN-030189
- AM84929
- AN-5281
- BCP9000405
- CCG-264775
- CID9809715
- CS-0104
- DB09079
- FM34144
- KS-1434
- NSC-756659
- NSC-757442
- NSC-800805
- RL05845
- SB11190
- SDCCGSBI-0654257.P002
- BIBF 1120; VARGATEF; INTEDANIB
- NCGC00263156-01
- NCGC00263156-02
- NCGC00263156-13
- NCGC00263156-14
- NCGC00263156-15
- NCGC00389321-03
- 4CA-0650
- AC-25071
- AK170374
- BC297819
- BN164249
- BP-44034
- HY-50904
- SC-85732
- SMR004701273
- SY034707
- US20250129067, Compound Nintedanib
- AB0035905
- AB1006397
- A8252
- B1022
- FT-0670358
- FT-0772497
- NS00040680
- NS00099369
- SW218301-2
- X7367
- Y0352
- EC-000.2311
- J2.815.614F
- A10137
- D10481
- EN300-188528
- (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- A893659
- F050741
- (Z)-Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- BRD-K49075727-001-01-0
- BRD-K49075727-001-08-5
- BRD-K49075727-001-09-3
- Q15149723
- Q27163267
- 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester
- methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
- Methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate
- methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
- Z2756516920
- (Z)-Methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)-phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- Methyl (3z)-3-{[(4-{methyl[(4-Methylpiperazin-1-Yl)acetyl]amino}phenyl)amino](Phenyl)methylidene}-2-Oxo-2,3-Dihydro-1h-Indole-6-Carboxylate
- methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate
- 1624587-84-3
- 417716-92-8
- Methyl (3Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylidene)-2-oxo-2,3-dihydro-1h-indole-6-carboxylate
- methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
- methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenyl-methylene]-2-oxo-indoline-6-carboxylate
- (3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid methyl ester
- (3Z)-2,3-Dihydro-3-[alpha-[[4-[methyl[2-(4-methylpiperazino)acetyl]amino]phenyl]amino]benzylidene]-2-oxo-1H-indole-6-carboxylic acid methyl ester
- (E)-methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-; 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)- (9CI); BIBF 1120; Nintedanib; Ofev; Vargatef
- 2,3-Dihydro-3[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid methyl ester
- 3-[[4-[methyl-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylic acid methyl ester
- 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone
- methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate
- methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-
- Methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carb oxylate
- Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate
- Methyl (Z)-3-[[[4-[N-Methyl-2-(4-methyl-1-piperazinyl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate
- Methyl 2-hydroxy-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-3H-indole-6-carboxylate
- methyl 2-hydroxy-3-[(E)-({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}imino)(phenyl)methyl]-1H-indole-6-carboxylate
- Methyl 2-hydroxy-3-[{4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]anilino}(phenyl)methylidene]-3H-indole-6-carboxylate
- methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenyl-carbonimidoyl]-1H-indole-6-carboxylate
- Methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- methyl 3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
- methyl 3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenyl-methylene]-2-oxo-indoline-6-carboxylate
- XIN