Chemical Compound

4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-Hydroxypropanoic Acid; CHIR 258; TKI 258;

Name: 4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-Hydroxypropanoic Acid; CHIR 258; TKI 258;
Brand: EASY CDMO
SKU: 135398510

CAS Registry Number 405169-16-6

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Primary record

4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-Hydroxypropanoic Acid; CHIR 258; TKI 258;

库存: 9,399 克
纯度: 98.3 %
CAS: 405169-16-6

化合物标识与属性

CAS: 405169-16-6
PubChem CID: 135398510
SMILES: CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N
Canonical SMILES: CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1

名称与同义词

Dovitinib
405169-16-6
CHIR-258
Dovitinib lactate
Dovitinib [INN]
dovitinibum
Dovitinib base
TKI-258
Chir 258
Dovitinib, Free Base
CHIR258
Dovitinib, TKI258
Dovitinib (TKI-258)
Dovitinib (TKI-258, CHIR-258)
Kinome_1513
TKI258
CHIR-258(Dovitinib)
RefChem:590385
GFKI-258
UNII-I35H55G906
D07OZR
D0K3OY
DOVITINIB [WHO-DD]
C21H21FN6O
CHEMBL522892
2-Chloro-4-phenylpyrimidine
NVP-TKI258
MFCD10565680
CHEMBL4578973
cc-257
MLS006009991
I35H55G906
SCHEMBL172687
SCHEMBL949705
TKI 258
PIQCTGMSNWUMAF-UHFFFAOYSA-N
TK-258
GTPL5962
orb1300899
SCHEMBL9975396
SCHEMBL10330209
SCHEMBL20399550
SCHEMBL23876106
SCHEMBL29352967
SCHEMBL29424010
SCHEMBL30567813
BDBM25118
CHEBI:91395
CTK4I3259
KS-00000XGE
AOB6730
QCR-175
SYN1029
MFCD11870802
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
BCPP000286
BDBM153731
CHIR-258(Dovitinib,TKI258)
Dovitinib,TKI258, CHIR-258
DTXSID901025925
GLXC-05017
HMS3295E21
HMS3651E03
BCP01981
EX-A2051
PLX 3397
PLX-3397
ZINC3816310
CHIR258 (TKI-258)
ABP000878
BDBM50507579
NSC759661
NSC800092
NSC807408
s1018
ZINC18710083
Dovitinib; TKI-258; CHIR-258
AKOS005146311
AKOS015951093
ZINC100270141
ACN-050735
AN-3572
AN-5286
BCP9000518
CCG-264778
CID9886808
CID9977819
CS-0120
DB05928
FD22602
NSC-759661
NSC-800092
NSC-807408
PB13248
RL03559
SB20297
SDCCGSBI-0654439.P001
CID 9977819
NCGC00249685-01
NCGC00249685-02
NCGC00249685-11
AC-32059
AJ-45710
AK326179
AS-19556
BC251851
HY-50905
SC-54643
SMR004701066
SY046274
AB0007885
AB1008445
A2168
FT-0667782
NS00069284
SW219787-1
Y0345
804551-71-1
EC-000.2257
J2.267.848E
TKI-258, Dovitinib, CHIR258, TKI258
4-Amino-5-Fluoro-3-(6-(4-Methylpiperazin-1-yl)-1H-Benzo[D]Imidazol-2-yl)Quinolin-2(1H)-One
A11411
A24080
C75053
Q-4437
169A166
196472-EP2270000A1
2(1H)-Quinolinone,4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
326D834
1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one
S14-2675
BRD-K85402309-001-01-7
BRD-K85402309-001-06-6
BRD-K85402309-001-07-4
BRD-K85402309-043-01-9
BRD-K85402309-389-03-2
BRD-K85402309-389-04-0
BRD-K85402309-406-01-8
Q27077102
Q27163255
Q27453625
1027263-12-2
4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-
915769-50-5
4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one
B2693-091881
(3Z)-4-Amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]-2(3H)-quinolinone
4-AMINO-5-FLUORO-3-[ 5- (4-METHYLPIPERAZIN-1-YL)-1
(3E)-4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1,3-dihydrobenzimidazol-2-ylidene]quinolin-2-one
(3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1,3-dihydrobenzimidazol-2-ylidene]quinolin-2-one
1447274-99-8
4-AMINO-5-FLUORO-3-[ 5- (4-METHYLPIPERAZIN-1-YL)-1H-BENZIMIDAZOL-2-YL]QUINOLIN-2(1H)-ONE
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one
4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one
4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2 (1h)-one
4-Amino-5-fluoro-3-[5-(4-methylpiperazino)-3H-benzoimidazole-2-yl]quinoline-2(1H)-one
4-amino-5-fluoro-3-[6(4-methyl-1-piperazinyl)-1h-benzimidazol-2-yl]-2(1h)-quinolinone
4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-2-benzimidazolyl]quinolin-2(1H)-one
4-amino-5-fluoro-3-[6-(4-methyl-piperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one
4-Amino-5-fluoro-3-[6-(4-methylpiperazino)-1H-benzoimidazole-2-yl]-2(1H)-quinolinone
(3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,3-dihydrobenzimidazol-2-ylidene]carbostyril
(E)-4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)quinolin-2(3H)-one
(Z)-4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)quinolin-2(3H)-one
3-[6-(4-Methyl-1-piperazinyl)-1H-benzoimidazole-2-yl]-4-amino-5-fluoroquinoline-2(1H)-one
3-[6-(4-Methylpiperazino)-1H-benzoimidazole-2-yl]-4-amino-5-fluoro-1,2-dihydroquinoline-2-one
38O
4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene)-2,3-dihydroquinolin-2-one
4-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl)-1,2-dihydroquinolin-2-one
4-AMINO-5-FLUORO-3-(6-(4-METHYLPIPERAZIN-1-YL)-1H-BENZIMIDAZOL-2-YL)QUINOLIN-2(1H)-ONE
4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1,3-dihydrobenzimidazol-2-ylidene]-2-quinolinone
4-AMINO-5-FLUORO-3-[5-(4-METHYLPIPERAZIN-1-YL)-1H-1,3-BENZODIAZOL-2-YL]-1H-QUINOLIN-2-ONE
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one?Dovitinib base
4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]-2,3-dihydroquinolin-2-one
4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-Hydroxypropanoic Acid; CHIR 258; TKI 258;
692737-80-7
928326-83-4
Dovitinib; 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one