Chemical Compound

Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-; N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide; G 02442104; GSK 1120212; GSK 212; JTP 74057; Mekinist; N-[3-[3-Cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; Trametinib; Trametinib related; GSK 1120212A

CAS Registry Number 871700-17-3
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Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-; N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide; G 02442104; GSK 1120212; GSK 212; JTP 74057; Mekinist; N-[3-[3-Cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; Trametinib; Trametinib related; GSK 1120212A 结构式
Primary record

Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-; N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide; G 02442104; GSK 1120212; GSK 212; JTP 74057; Mekinist; N-[3-[3-Cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; Trametinib; Trametinib related; GSK 1120212A

库存
1,349 克
纯度
98.8 %
CAS
871700-17-3

化合物标识与属性

CAS
871700-17-3
PubChem CID
11707110
SMILES
CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5
Canonical SMILES
CC(=O)Nc1cccc(-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c32)c1

名称与同义词

  • Trametinib
  • Mekinist
  • 871700-17-3
  • GSK1120212
  • trametinibum
  • Trametinib?
  • GSK-1120212
  • Trametinib (GSK1120212)
  • Trametinib [USAN]
  • JTP 74057
  • T-nib
  • JTP-74057
  • Trametinib (USAN)
  • GSK 1120212
  • TMT212
  • Trametinib (Standard)
  • Trametinib [USAN:INN]
  • GSK212
  • RefChem:57975
  • TRAMETINIB [MI]
  • MFCD17215075
  • TRAMETINIB [INN]
  • TMT-212
  • C26H23FIN5O4
  • TRAMETINIB [VANDF]
  • cc-37
  • CHEBI:75998
  • D04XVN
  • D0F5RQ
  • UNII-33E86K87QN
  • Trametinib (MEK inhibitor)
  • 33E86K87QN
  • TRAMETINIB [WHO-DD]
  • JTP74057
  • SCHEMBL170938
  • GTPL6495
  • orb1306425
  • QCR-39
  • GSK1120212 (Trametinib)
  • CHEMBL2103875
  • MEK Inhibitor GSK1120212
  • SCHEMBL29355100
  • SCHEMBL29363416
  • TRAMETINIB DIMETHYL SULFOXIDE
  • GSK1120212B
  • EX-A022
  • L01XE25
  • LIRYPHYGHXZJBZ-UHFFFAOYSA-N
  • BCPP000218
  • DTXSID901007381
  • GLXC-90070
  • HMS3295I05
  • HMS3656J11
  • HMS5081N13
  • AOB87707
  • BCP02307
  • ABP000312
  • AN-539
  • BDBM50531540
  • EBC-17166
  • HY-10999R
  • NSC758246
  • NSC800956
  • RW4149
  • s2673
  • ZINC43100709
  • AKOS015850628
  • N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide
  • ACN-041327
  • AM90271
  • CCG-264976
  • CS-0060
  • DB08911
  • EX-5957
  • FC34128
  • NSC-758246
  • NSC-800956
  • RL05418
  • SB16553
  • SDCCGSBI-0646933.P001
  • Trametinib (GSK1120212JTP 74057)
  • CID11707110
  • NCGC00263180-01
  • NCGC00263180-07
  • NCGC00263180-14
  • 4CA-0583
  • AC-25891
  • AK174783
  • AS-19382
  • BC638742
  • BP-44059
  • CID 11707110
  • CID:11707110
  • HY-10999
  • SC-85458
  • SY067882
  • SID:160778567
  • AB0008115
  • A3018
  • FT-0688438
  • NS00040692
  • SW218089-2
  • X7454
  • J3.135.455B
  • KS-00000002
  • A11029
  • A25168
  • D10175
  • GSK1120212 - JTP-74057
  • S-7800
  • GSK-1120212/GSK1120212/
  • N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide
  • C560077
  • EN300-25299821
  • GSK1120212,JTP-74057, GSK212
  • SR-01000941589
  • N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide
  • Q7833138
  • SR-01000941589-1
  • BRD-K12343256-001-01-4
  • BRD-K12343256-001-08-9
  • BRD-K12343256-001-11-3
  • BRD-K12343256-001-14-7
  • BRD-K12343256-001-18-8
  • N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amin
  • Trametinib, 98%, a MEK1/2 inhibitor - 10MG 10mg
  • JTP-74057, 871700-17-3
  • N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
  • B0084-307744
  • N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodo-anilino)-6,8-dimethyl-2,4,7-trioxo-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
  • N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-1H,2H,3H,4H,6H,7H-pyrido[4,3-d]pyrimidin-1-yl}phenyl)acetamide
  • 1187431-43-1
  • 3 -[3-Cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidine-1(2H)-yl]acetoanilide
  • Acetamide, N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-3,4,6,7-tetrahydro-6,8- dimethyl-2,4,7-trioxopyrido(4,3-d)pyrimidin-1(2H)-yl)phenyl)-
  • Acetamide, N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido(4,3-d)pyrimidin-1(2H)-yl)phenyl)-
  • Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-
  • Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-; N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide; G 02442104; GSK 1120212; GSK 212; JTP 74057; Mekinist; N-[3-[3-Cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; Trametinib; Trametinib related; GSK 1120212A
  • Acetamide,N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-
  • N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-1H,2H,3H,4H,6H,7H-pyrido(4,3-d)pyrimidin-1-yl)phenyl)acetamide
  • N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7- tetrahydropyrido(4,3-d)pyrimidin-1(2H)-yl)phenyl)acetamide
  • N-(3-(3-CYCLOPROPYL-5-((2-FLUORO-4-IODOPHENYL)AMINO)-6,8-DIMETHYL-2,4,7-TRIOXO-3,4,6,7-TETRAHYDROPYRIDO(4,3-D)PYRIMIDIN-1(2H)-YL)PHENYL)ACETAMIDE
  • N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxopyrido(3,4-e)pyrimidin-1-yl)phenyl)acetamide
  • N-(3-(3-Cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)pheny l)acetamide
  • N-(3-(3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide
  • N-(3-{3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7- tetrahydropyrido(4,3-d)pyrimidin-1(2H)-yl}phenyl)acetamide
  • N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl}phenyl)acetamide
  • N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4, 7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
  • n-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyr
  • N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidine-1(2H)-yl]phenyl]acetamide
  • N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide
  • N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidine-1(2H)-yl]phenyl]acetamide
  • N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxopyrido[3,4-e]pyrimidin-1-yl]phenyl]acetamide
  • N-{3-[3-Cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl}ethanimidic acid
  • N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide
  • QOM